Sudafed and Cholestyramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sudafed (pseudoephedrine hydrochloride) and Cholestyramine (cholestyramine). Common drug interactions include cardiac valve disease among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Sudafed and Cholestyramine. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Sudafed?

Sudafed has active ingredients of pseudoephedrine hydrochloride. It is often used in nasal congestion. eHealthMe is studying from 12,944 Sudafed users. Check the latest studies of Sudafed.

What is Cholestyramine?

Cholestyramine has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 9,893 Cholestyramine users. Check the latest studies of Cholestyramine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

34 people who take Sudafed and Cholestyramine together, and have interactions are studied.

Sudafed and Cholestyramine drug interactions.

What are the common drug interactions of Sudafed and Cholestyramine, by gender? *:

female:

Cardiac valve disease (heart valve disease)
Cystitis (inflammation of the wall of the bladder)
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Drug ineffective
Dyslipidaemia (abnormal amount of lipids)
Dysphagia (a condition in which swallowing is difficult or painful)
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Febrile neutropenia (fever with reduced white blood cells)

male:

Hypotension (abnormally low blood pressure)
Leukaemia (blood or bone marrow cancer)
Fatigue (feeling of tiredness)
Haemodynamic instability (disturbances in the blood movement in our body)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic failure (liver failure)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Klebsiella infection
Livedo reticularis (a lace-like purplish discoloration of the skin)
Pancreatitis (inflammation of pancreas)

What are the common drug interactions of Sudafed and Cholestyramine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Fatigue (feeling of tiredness)
Insomnia (sleeplessness)
Polydipsia (excessive thirst)
Thirst
Abdominal pain upper
Anxiety
Balance disorder
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Flushing (the warm, red condition of human skin)

30-39:

Drug ineffective
Foetal death (death of foetus)
Pregnancy
Sinusitis (inflammation of sinus)

40-49:

n/a

50-59:

Neuropathy peripheral (surface nerve damage)
Pain

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Hypotension (abnormally low blood pressure)
Injury
Nausea (feeling of having an urge to vomit)
Proctalgia (pain in the rectum)
Arthralgia (joint pain)
Asthenia (weakness)
Blood pressure fluctuation
Hypovolaemia (a decreased volume of circulating blood in the body)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 29.41%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 26.47%
Multiple Myeloma (cancer of the plasma cells): 7 people, 20.59%
Pain: 6 people, 17.65%
Nausea (feeling of having an urge to vomit): 4 people, 11.76%
Immunodeficiency Common Variable: 4 people, 11.76%
Constipation: 4 people, 11.76%
Vitamin B12 Deficiency: 3 people, 8.82%
Viral Upper Respiratory Tract Infection: 3 people, 8.82%
Nasopharyngitis (inflammation of the nasopharynx): 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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