Sudafed and Sumatriptan succinate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sudafed (pseudoephedrine hydrochloride) and Sumatriptan succinate (sumatriptan succinate). Common drug interactions include influenza among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Sudafed and Sumatriptan succinate. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.
What is Sudafed?
Sudafed has active ingredients of pseudoephedrine hydrochloride. It is often used in nasal congestion. eHealthMe is studying from 12,944 Sudafed users. Check the latest studies of Sudafed.
What is Sumatriptan succinate?
Sumatriptan succinate has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 9,731 Sumatriptan succinate users. Check the latest studies of Sumatriptan succinate.
65 people who take Sudafed and Sumatriptan succinate together, and have interactions are studied.

What are the common drug interactions of Sudafed and Sumatriptan Succinate, by gender? *:
female:
- Influenza
- Insomnia (sleeplessness)
- Memory impairment
- Muscle spasms (muscle contraction)
- Muscular weakness (muscle weakness)
- Neoplasm malignant (cancer tumour)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Thyroid cancer
- Headache (pain in head)
- Seasonal allergy (allergic condition due to certain season)
male:
- Arthralgia (joint pain)
- Tendonitis (a condition that causes pain and swelling of tendons)
- Osteoporosis (bones weak and more likely to break)
- Pain
- Coeliac disease (simple food intolerance)
- Depression
- Drug ineffective
- Hyperkalaemia (damage to or disease of the kidney)
- Rib fracture
- Renal impairment (severely reduced kidney function)
What are the common drug interactions of Sudafed and Sumatriptan Succinate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain upper
- Back pain
- Bipolar disorder (mood disorder)
- Chest pain
- Chills (felling of cold)
- Hot flush (sudden feelings of heat)
- Hyperhidrosis (abnormally increased sweating)
- Hypersensitivity
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Nausea (feeling of having an urge to vomit)
30-39:
n/a
40-49:
- Arthralgia (joint pain)
- Tendonitis (a condition that causes pain and swelling of tendons)
- Bacterial infection
- Drug ineffective
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Pulmonary function test decreased
- Suicide attempt
50-59:
- Fatigue (feeling of tiredness)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Balance disorder
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
- Decreased immune responsiveness
- Gait disturbance
- Intervertebral discitis (infection in the intervertebral disc space)
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Neuralgia (pain in one or more nerves)
- Renal impairment (severely reduced kidney function)
60+:
- Fungal infection
- Seasonal allergy (allergic condition due to certain season)
- Anxiety
- Blood creatinine increased
- Bone density decreased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Conjunctivitis (pink eye)
- Death
- Drug hypersensitivity
- Emotional distress
What are the existing conditions these people have? *
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 14 people, 21.54%
- Hereditary Angioedema (recurrent episodes of severe swelling): 8 people, 12.31%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 10.77%
- Immunodeficiency Common Variable: 7 people, 10.77%
- Pain: 5 people, 7.69%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 7.69%
- Bipolar Disorder (mood disorder): 5 people, 7.69%
- Cystic Fibrosis (disease of the secretary glands): 4 people, 6.15%
* Approximation only. Some reports may have incomplete information.
Do you take Sudafed and Sumatriptan succinate?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sudafed (12,944 reports)
- Sumatriptan succinate (9,731 reports)
Browse all drug interactions of Sudafed and Sumatriptan succinate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sudafed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sumatriptan succinate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sudafed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sumatriptan succinate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pseudoephedrine hydrochloride and sumatriptan succinate (the active ingredients of Sudafed and Sumatriptan succinate, respectively), and Sudafed and Sumatriptan succinate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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