Sular and Nitrostat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sular (nisoldipine) and Nitrostat (nitroglycerin). Common drug interactions include chronic kidney disease among females and atrioventricular block first degree among males.

The phase IV clinical study analyzes what interactions people have when they take Sular and Nitrostat. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Sular?

Sular has active ingredients of nisoldipine. It is often used in high blood pressure. eHealthMe is studying from 1,757 Sular users. Check the latest studies of Sular.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

On Jul, 06, 2026

21 people who take Sular and Nitrostat together, and have interactions are studied.

What are the common drug interactions of Sular and Nitrostat, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Pain in limb
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Cardiac arrest
Contrast media reaction (reaction associated with the use of intravenous contrast material during radiology)
Dyspnoea (difficult or laboured respiration)
Electrocardiogram qt prolonged
Endotracheal intubation complication

male:

Atrioventricular block first degree (heart block first degree)
Dysphagia (a condition in which swallowing is difficult or painful)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Amputation
Arteritis (inflammation of the walls of arteries)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood creatinine increased
Dyspnoea (difficult or laboured respiration)
Epistaxis (bleed from the nose)
Sleep disorder

What are the common drug interactions of Sular and Nitrostat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Decreased activity
Emotional distress
Hand fracture
Osteoporosis (bones weak and more likely to break)
Pain
Chronic kidney disease
Femoral artery occlusion (obstruction in artery of femur)

60+:

Atrioventricular block first degree (heart block first degree)
Chronic kidney disease
Fatigue (feeling of tiredness)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Syncope (loss of consciousness with an inability to maintain postural tone)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Amputation
Arteritis (inflammation of the walls of arteries)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood creatinine increased

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 33.33%
Migraine (headache): 3 people, 14.29%
Gastric Ph Decreased: 3 people, 14.29%
Pain: 3 people, 14.29%
Sinus Disorder (disease of sinus): 2 people, 9.52%
Haemorrhage (bleeding): 2 people, 9.52%
Appetite Disorder (abnormal eating habits): 2 people, 9.52%
Asthma: 2 people, 9.52%
Blood Pressure Abnormal: 2 people, 9.52%
Bone Density Decreased: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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