Sular and Zofran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sular (nisoldipine) and Zofran (ondansetron hydrochloride). Common drug interactions include nasopharyngitis among females and multiple sclerosis among males.

The phase IV clinical study analyzes what interactions people have when they take Sular and Zofran. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Sular?

Sular has active ingredients of nisoldipine. It is often used in high blood pressure. eHealthMe is studying from 1,757 Sular users. Check the latest studies of Sular.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

On Jul, 28, 2026

20 people who take Sular and Zofran together, and have interactions are studied.

What are the common drug interactions of Sular and Zofran, by gender? *:

female:

Nasopharyngitis (inflammation of the nasopharynx)
Nervousness
Oedema peripheral (superficial swelling)
Pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Post procedural complication
Pyelonephritis (inflammation of kidney caused by bacteria)
Retroperitoneal haemorrhage (bleeding between the peritoneum and the posterior abdominal wall)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Sinusitis (inflammation of sinus)

male:

Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Fatigue (feeling of tiredness)
International normalised ratio increased
Pleural effusion (water on the lungs)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Respiratory distress (difficulty in breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)
Asthenia (weakness)
Chills (felling of cold)
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Sular and Zofran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Nervousness
Pain
Pneumonia
Pulmonary oedema (fluid accumulation in the lungs)
Pyelonephritis (inflammation of kidney caused by bacteria)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Sinusitis (inflammation of sinus)
Tardive dyskinesia (a disorder that involves involuntary movements)
Urinary tract infection
Vaginal haemorrhage (vaginal bleeding)

30-39:

n/a

40-49:

n/a

50-59:

Cardiac arrest
Collapse (sudden functional breakdown)
Dehydration (dryness resulting from the removal of water)
Loss of consciousness
Vasovagal attack (malaise mediated by the vagus nerve)
Hypotension (abnormally low blood pressure)
Pulse absent
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Syncope (loss of consciousness with an inability to maintain postural tone)
Anger

60+:

Fatigue (feeling of tiredness)
Asthenia (weakness)
Dysphagia (a condition in which swallowing is difficult or painful)
Headache (pain in head)
Hypokalaemia (low potassium)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Pleural effusion (water on the lungs)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Respiratory distress (difficulty in breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 25.00%
Pancreatic Insufficiency: 2 people, 10.00%
Nausea And Vomiting: 2 people, 10.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 10.00%
Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 5.00%
Pancreatic Carcinoma (pancreatic cancer): 1 person, 5.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.00%
Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 5.00%
Infection: 1 person, 5.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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