Sulfamethoxazole and Aredia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sulfamethoxazole (sulfamethoxazole) and Aredia (pamidronate disodium). Common drug interactions include anxiety among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Sulfamethoxazole and Aredia. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Sulfamethoxazole?

Sulfamethoxazole has active ingredients of sulfamethoxazole. It is often used in urinary tract infection. eHealthMe is studying from 13,360 Sulfamethoxazole users. Check the latest studies of Sulfamethoxazole.

What is Aredia?

Aredia has active ingredients of pamidronate disodium. It is often used in breast cancer. eHealthMe is studying from 15,364 Aredia users. Check the latest studies of Aredia.



On Jul, 18, 2026

72 people who take Sulfamethoxazole and Aredia together, and have interactions are studied.

Sulfamethoxazole and Aredia drug interactions.

What are the common drug interactions of Sulfamethoxazole and Aredia, by gender? *:

female:

  1. Anxiety
  2. Mastication disorder (disease of chewing food)
  3. Osteopenia (a condition where bone mineral density is lower than normal)
  4. Pain in jaw
  5. Physical disability
  6. Osteonecrosis of jaw (death of bone of jaw)
  7. Dental caries
  8. Tooth extraction
  9. Emotional distress
  10. Gastritis (inflammation of stomach)

male:

  1. Pain
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  3. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  4. Hypertension (high blood pressure)
  5. Bone disorder
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Dyspnoea (difficult or laboured respiration)
  8. Nausea (feeling of having an urge to vomit)
  9. Pulmonary oedema (fluid accumulation in the lungs)
  10. Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Sulfamethoxazole and Aredia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Abdominal pain
  2. Actinic keratosis (skin disease due to sun exposure)
  3. Anaemia (lack of blood)
  4. Appendicitis (inflammation of the appendix)
  5. Bone disorder
  6. Cardiac failure congestive
  7. Cardiac murmur (an heart sound in valve abnormality)
  8. Cardiomyopathy (weakening of the heart muscle)
  9. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  10. Cerebral calcification (abnormal deposits of calcium in certain areas of the brain)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Dental caries
  2. Impaired healing
  3. Loose tooth
  4. Pain
  5. Swelling
  6. Appendicitis (inflammation of the appendix)
  7. Bone disorder
  8. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  9. Emotional distress
  10. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)

50-59:

  1. Renal cyst (kidney cyst)
  2. Vomiting
  3. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  4. Nausea (feeling of having an urge to vomit)
  5. Atelectasis (partial or complete collapse of the lung)
  6. Abdominal pain lower
  7. Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
  8. Balance disorder
  9. Benign prostatic hyperplasia (benign enlargement of the prostate)
  10. Blood immunoglobulin a decreased

60+:

  1. Anaemia (lack of blood)
  2. Anxiety
  3. Pain in jaw
  4. Hypertension (high blood pressure)
  5. Osteonecrosis of jaw (death of bone of jaw)
  6. Sinusitis (inflammation of sinus)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Cardiac failure congestive
  9. Encephalopathy (functioning of the brain is affected by some agent or condition)
  10. Gingival swelling (gums swelling)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 34 people, 47.22%
  2. Pain: 17 people, 23.61%
  3. Metastases To Bone (cancer spreads to bone): 16 people, 22.22%
  4. Nausea (feeling of having an urge to vomit): 10 people, 13.89%

* Approximation only. Some reports may have incomplete information.

Do you take Sulfamethoxazole and Aredia?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sulfamethoxazole and Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sulfamethoxazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aredia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sulfamethoxazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aredia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole and pamidronate disodium (the active ingredients of Sulfamethoxazole and Aredia, respectively), and Sulfamethoxazole and Aredia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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