Sulfamethoxazole and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sulfamethoxazole (sulfamethoxazole) and Compazine (prochlorperazine maleate). Common drug interactions include bronchitis among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Sulfamethoxazole and Compazine. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Sulfamethoxazole?

Sulfamethoxazole has active ingredients of sulfamethoxazole. It is often used in urinary tract infection. eHealthMe is studying from 13,360 Sulfamethoxazole users. Check the latest studies of Sulfamethoxazole.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

On Jul, 16, 2026

42 people who take Sulfamethoxazole and Compazine together, and have interactions are studied.

Sulfamethoxazole and Compazine drug interactions.

What are the common drug interactions of Sulfamethoxazole and Compazine, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiomegaly (increased size of heart than normal)
Carotid artery stenosis (narrowing of carotid artery)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Chills (felling of cold)
Chronic kidney disease
Cough
Cytomegalovirus test positive
Decreased appetite
Delusion (a false belief or opinion)

male:

Pneumonia
Death
Asthenia (weakness)
Back pain
Chills (felling of cold)
Chronic kidney disease
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Diplopia (double vision)
Disturbance in attention

What are the common drug interactions of Sulfamethoxazole and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease

30-39:

n/a

40-49:

Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Erythema (redness of the skin)
Myalgia (muscle pain)
Rash
Rash macular (small, flat red spots)
Dehydration (dryness resulting from the removal of water)
Dizziness
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)

50-59:

Middle ear effusion (fluid in middle ear)
Pyrexia (fever)
Road traffic accident
Sinus disorder (disease of sinus)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Upper respiratory tract infection
Cellulitis (infection under the skin)
Diarrhoea
Hospitalisation

60+:

Pneumonia
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Local swelling (swelling at the site of some application of substance or injury)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Plasma cell myeloma (cancer that begins in plasma cells)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Productive cough
Pyrexia (fever)
Rash

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 22 people, 52.38%
High Blood Pressure: 7 people, 16.67%
Back Pain: 6 people, 14.29%
Immunodeficiency Common Variable: 6 people, 14.29%
Dyspnea (difficult or laboured breathing): 5 people, 11.90%
Sleep Disorder: 5 people, 11.90%
Nausea (feeling of having an urge to vomit): 5 people, 11.90%
Stress And Anxiety: 5 people, 11.90%
Floppy Eyelid Syndrome (eyelid spontaneously inverts and is characterized by loose upper eyelids): 5 people, 11.90%
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 5 people, 11.90%

* Approximation only. Some reports may have incomplete information.

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