Sulfamethoxazole and Thalidomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sulfamethoxazole (sulfamethoxazole) and Thalidomide (thalidomide). Common drug interactions include vomiting among females and bipolar disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Sulfamethoxazole and Thalidomide. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Sulfamethoxazole?

Sulfamethoxazole has active ingredients of sulfamethoxazole. It is often used in urinary tract infection. eHealthMe is studying from 13,360 Sulfamethoxazole users. Check the latest studies of Sulfamethoxazole.

What is Thalidomide?

Thalidomide has active ingredients of thalidomide. eHealthMe is studying from 16,473 Thalidomide users. Check the latest studies of Thalidomide.

On Jul, 30, 2026

78 people who take Sulfamethoxazole and Thalidomide together, and have interactions are studied.

Sulfamethoxazole and Thalidomide drug interactions.

What are the common drug interactions of Sulfamethoxazole and Thalidomide, by gender? *:

female:

Vomiting
Hypertension (high blood pressure)
Osteopenia (a condition where bone mineral density is lower than normal)
Injury
Mastication disorder (disease of chewing food)
Pain in jaw
Physical disability
Spinal osteoarthritis (joint cartilage loss in spine)
Mucosal inflammation (infection of mucous membrane)
Nausea (feeling of having an urge to vomit)

male:

Bipolar disorder (mood disorder)
Pneumonia
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis of jaw (death of bone of jaw)
Pain
Pulmonary oedema (fluid accumulation in the lungs)
Balance disorder

What are the common drug interactions of Sulfamethoxazole and Thalidomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Bipolar disorder (mood disorder)
Abdominal pain upper
Hair follicle tumour benign
Hepatosplenic t-cell lymphoma (neoplasm comprising medium-sized cytotoxic t-cells that show a significant sinusoidal infiltration in the liver, spleen, and bone marrow)
Hypotension (abnormally low blood pressure)
Lymphoproliferative disorder (a medical condition in which the immune system makes too many white blood cells)
Pyrexia (fever)
Splenomegaly (enlargement of spleen)
T-cell lymphoma (a blood cell cancer)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

20-29:

Breast cancer in situ
Human herpesvirus 8 infection
Hypoxia (low oxygen in tissues)
Kaposi's sarcoma (a tumour caused by human herpes virus)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Herpes zoster
Viral haemorrhagic cystitis (lower urinary tract symptoms that include haematuria and irritative voiding symptoms)
Bk virus infection
Bone marrow failure

30-39:

Anxiety
Bone disorder
Dental caries
General physical health deterioration (weak health status)
Lymphadenopathy (disease or enlargement of lymph nodes)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Pain
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Swelling
Vomiting

40-49:

Oedema peripheral (superficial swelling)
Abdominal distension
Abdominal pain
Abscess (pus)
Acetabulum fracture (socket of the hip joint- fracture)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Agitation (state of anxiety or nervous excitement)
Anaemia (lack of blood)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Anxiety

50-59:

Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Back pain
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Bone disorder
Cardiomegaly (increased size of heart than normal)
Discomfort
Ear pain
Emotional distress

60+:

Anaemia (lack of blood)
Anxiety
Gingival swelling (gums swelling)
Mitral valve calcification (calcium deposit in mitral valve)
Spinal osteoarthritis (joint cartilage loss in spine)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Polyp
Cataract (clouding of the lens inside the eye)
Herpes zoster
Osteonecrosis of jaw (death of bone of jaw)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 42 people, 53.85%
Pain: 13 people, 16.67%
Metastases To Bone (cancer spreads to bone): 12 people, 15.38%
Medulloblastoma Recurrent (reoccurrence of a fast-growing, high-grade tumour that always begins in the cerebellum): 10 people, 12.82%
Blood Growth Hormone Decreased: 10 people, 12.82%
Constipation: 5 people, 6.41%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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