Sulfasalazine and Zerit drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sulfasalazine (sulfasalazine) and Zerit (stavudine). Common drug interactions include abdominal pain among females and angina pectoris among males.
The phase IV clinical study analyzes what interactions people have when they take Sulfasalazine and Zerit. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Sulfasalazine?
Sulfasalazine has active ingredients of sulfasalazine. It is often used in rheumatoid arthritis. eHealthMe is studying from 96,787 Sulfasalazine users. Check the latest studies of Sulfasalazine.
What is Zerit?
Zerit has active ingredients of stavudine. eHealthMe is studying from 9,912 Zerit users. Check the latest studies of Zerit.
15 people who take Sulfasalazine and Zerit together, and have interactions are studied.

What are the common drug interactions of Sulfasalazine and Zerit, by gender? *:
female:
- Abdominal pain
- Abdominal tenderness
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
- Fatigue (feeling of tiredness)
- Haemoglobin decreased
- Lethargy (tiredness)
- Pancreatitis (inflammation of pancreas)
- Pancreatitis necrotising (inflammation of the pancreas cause death of tissue in pancreas)
- Vomiting
male:
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Coronary artery thrombosis (clot formation in coronary artery)
- Blood cholesterol increased
- Blood pressure decreased
- Blood triglycerides increased
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Confusion
- Hepatomegaly (abnormal enlargement of the liver)
- Hypotonia neonatal (low muscle tone in neonatal)
- Lipase increased
What are the common drug interactions of Sulfasalazine and Zerit, by age (0-1 to 60+)? *:
0-1:
- Hepatomegaly (abnormal enlargement of the liver)
- Hypotonia neonatal (low muscle tone in neonatal)
- Neutropenia neonatal (an abnormally low number of neutrophils in below a month baby)
- Anaemia macrocytic (a macrocytic class of anaemia)
- Drug exposure during pregnancy
- Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
- Hypertonia neonatal (abnormal increase in muscle tension and a reduced ability of a muscle to stretch in neonatal)
- Neonatal disorder (disease of neonates)
- Thrombocythaemia (an increased number of platelets in the circulating blood)
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Lactic acidosis (low ph in body tissues)
- Vomiting
40-49:
n/a
50-59:
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Coronary artery thrombosis (clot formation in coronary artery)
- Coronary artery stenosis (narrowing of coronary artery)
- Asphyxia (a condition in which there is an extreme decrease in the concentration of oxygen in the body)
- Pancreatitis (inflammation of pancreas)
- Apnoea (suspension of external breathing)
- Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
- Blood creatine phosphokinase increased
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Gastritis (inflammation of stomach)
60+:
- Abdominal pain
- Acute circulatory failure (shock)
- Lipase increased
- Pancreatitis acute (sudden inflammation of pancreas)
- Pulmonary oedema (fluid accumulation in the lungs)
- Renal failure (kidney dysfunction)
- Vomiting
- Atelectasis (partial or complete collapse of the lung)
- Blood amylase increased
- Blood cholesterol increased
What are the existing conditions these people have? *
- Hiv Infection: 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Sulfasalazine and Zerit?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sulfasalazine (96,787 reports)
- Zerit (9,912 reports)
Browse all drug interactions of Sulfasalazine and Zerit:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sulfasalazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zerit:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sulfasalazine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zerit and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on sulfasalazine and stavudine (the active ingredients of Sulfasalazine and Zerit, respectively), and Sulfasalazine and Zerit (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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