Sulindac and Hydrocodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sulindac (sulindac) and Hydrocodone (hydrocodone bitartrate; ibuprofen). Common drug interactions include abdominal pain among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Sulindac and Hydrocodone. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Sulindac?

Sulindac has active ingredients of sulindac. It is often used in rheumatoid arthritis. eHealthMe is studying from 3,824 Sulindac users. Check the latest studies of Sulindac.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

On Jul, 05, 2026

17 people who take Sulindac and Hydrocodone together, and have interactions are studied.

Sulindac and Hydrocodone drug interactions.

What are the common drug interactions of Sulindac and Hydrocodone, by gender? *:

female:

Abdominal pain
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Abdominal pain lower
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Arthralgia (joint pain)

male:

Abdominal pain upper
Asthenia (weakness)
Palpitations (feelings or sensations that your heart is pounding or racing)
Rash
Suicidal ideation
Tinnitus (a ringing in the ears)
Vision blurred
Weight increased
Blood urine present
Chest pain

What are the common drug interactions of Sulindac and Hydrocodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

40-49:

Abdominal pain upper
Asthenia (weakness)
Blindness
Dizziness
Headache (pain in head)
Hostility
Palpitations (feelings or sensations that your heart is pounding or racing)
Rash
Suicidal ideation
Tinnitus (a ringing in the ears)

50-59:

Bone density decreased
Chronic kidney disease
Emotional distress
Multiple fractures
Osteoporosis (bones weak and more likely to break)
Tooth loss
Bone pain
Nausea (feeling of having an urge to vomit)
Osteopenia (a condition where bone mineral density is lower than normal)
Pyrexia (fever)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Emotional distress
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Peripheral swelling
Staphylococcal infection (an infection with staphylococcus bacteria)
Surgery

What are the existing conditions these people have? *

Pain: 4 people, 23.53%
Hiv Infection: 4 people, 23.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 5.88%
Heart Attack: 1 person, 5.88%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.88%
Bacterial Infection: 1 person, 5.88%
Cardiac Disorder: 1 person, 5.88%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 5.88%
Chest Pain: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Sulindac and Hydrocodone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously