Sulindac and Oxaprozin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sulindac (sulindac) and Oxaprozin (oxaprozin). Common drug interactions include drug hypersensitivity among females and cor pulmonale chronic among males.

The phase IV clinical study analyzes what interactions people have when they take Sulindac and Oxaprozin. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Sulindac?

Sulindac has active ingredients of sulindac. It is often used in rheumatoid arthritis. eHealthMe is studying from 3,824 Sulindac users. Check the latest studies of Sulindac.

What is Oxaprozin?

Oxaprozin has active ingredients of oxaprozin. It is often used in joint pain. eHealthMe is studying from 1,578 Oxaprozin users. Check the latest studies of Oxaprozin.

On Jul, 15, 2026

25 people who take Sulindac and Oxaprozin together, and have interactions are studied.

Sulindac and Oxaprozin drug interactions.

What are the common drug interactions of Sulindac and Oxaprozin, by gender? *:

female:

Drug hypersensitivity
Pain in extremity
Back pain
Neck pain
Peripheral swelling
Drug ineffective
Aggression
Blood chloride decreased
Constipation
Deafness

male:

Cor pulmonale chronic (long lasting enlargement of the right ventricle of the heart)
Cough
Oedema (fluid collection in tissue)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Renal failure chronic (long lasting kidney dysfunction)
Restless legs syndrome (a powerful urge to move your legs)
Rosacea (a skin condition that causes facial redness)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Testicular failure (testicles cannot produce sperm or male hormones)
Erythema (redness of the skin)

What are the common drug interactions of Sulindac and Oxaprozin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Erythema (redness of the skin)
Feeling hot
Local swelling (swelling at the site of some application of substance or injury)
Oedema (fluid collection in tissue)

40-49:

n/a

50-59:

Drug hypersensitivity
Drug ineffective
Dry mouth
Heart rate increased
Infection
Lacrimal gland enlargement
Obesity (having too much body fat)
Oedema peripheral (superficial swelling)
Osteopenia (a condition where bone mineral density is lower than normal)
Pneumonia

60+:

Pain in extremity
Back pain
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypersensitivity
Hypertensive nephropathy (hypertensive renal disease)
Lower limb fracture
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the existing conditions these people have? *

Pain: 2 people, 8.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 8.00%
High Blood Cholesterol: 2 people, 8.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.00%
Blood Potassium Decreased: 2 people, 8.00%
Bedwetting: 2 people, 8.00%
Back Pain: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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