Sumatriptan succinate and Cardizem drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sumatriptan succinate (sumatriptan succinate) and Cardizem (diltiazem hydrochloride). Common drug interactions include nausea among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Sumatriptan succinate and Cardizem. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Sumatriptan succinate?
Sumatriptan succinate has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 9,731 Sumatriptan succinate users. Check the latest studies of Sumatriptan succinate.
What is Cardizem?
Cardizem has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 28,014 Cardizem users. Check the latest studies of Cardizem.
19 people who take Sumatriptan succinate and Cardizem together, and have interactions are studied.

What are the common drug interactions of Sumatriptan Succinate and Cardizem, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Sinusitis (inflammation of sinus)
- Upper respiratory tract infection
- Infusion related reaction
- Chronic kidney disease
- Hypoaesthesia (reduced sense of touch or sensation)
- Idiopathic thrombocytopenic purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)
- Oedema peripheral (superficial swelling)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Rhinitis allergic (inflammation of the nasal airways due to allergy)
male:
- Anxiety
- Completed suicide (act of taking one's own life)
- Depression
- Drug abuser
- Drug dependence
- Drug detoxification
- Pain
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
What are the common drug interactions of Sumatriptan Succinate and Cardizem, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Chronic kidney disease
- Glomerulonephritis membranoproliferative (a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (gbm) thickening)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Bladder discomfort
- Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
- Nephrocalcinosis (a condition in which calcium levels in the kidneys are increased)
- Renal impairment (severely reduced kidney function)
40-49:
- Anxiety
- Hypoaesthesia (reduced sense of touch or sensation)
- Pain
- Abdominal discomfort
- Abdominal pain upper
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anaemia (lack of blood)
- Asthenia (weakness)
- Back pain
- Blood creatinine increased
50-59:
- Idiopathic thrombocytopenic purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)
- Oedema peripheral (superficial swelling)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Rhinitis allergic (inflammation of the nasal airways due to allergy)
- Thrombocytopenia (decrease of platelets in blood)
- Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
- Face oedema (swelling of face)
- Genital pruritus female (itching in vagina)
- Mouth ulceration (mouth ulcers)
- Rash erythematous (redness of the skin)
60+:
- Headache (pain in head)
- Back pain
- Haematuria (presence of blood in urine)
- Hospitalisation
- Lower respiratory tract infection
- Parkinson's disease
- Pyrexia (fever)
- Respiratory tract infection
- Urinary tract infection
- Weight decreased
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 21.05%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 21.05%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.79%
- Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 15.79%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.53%
- Infection: 2 people, 10.53%
- Immunodeficiency Common Variable: 2 people, 10.53%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.53%
- Blood Pressure Abnormal: 2 people, 10.53%
- Pain: 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Sumatriptan succinate and Cardizem?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sumatriptan succinate (9,731 reports)
- Cardizem (28,014 reports)
Browse all drug interactions of Sumatriptan succinate and Cardizem:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sumatriptan succinate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cardizem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sumatriptan succinate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cardizem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on sumatriptan succinate and diltiazem hydrochloride (the active ingredients of Sumatriptan succinate and Cardizem, respectively), and Sumatriptan succinate and Cardizem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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