Sumatriptan succinate and Mucinex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sumatriptan succinate (sumatriptan succinate) and Mucinex (guaifenesin). Common drug interactions include epistaxis among females and renal impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Sumatriptan succinate and Mucinex. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Sumatriptan succinate?

Sumatriptan succinate has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 9,731 Sumatriptan succinate users. Check the latest studies of Sumatriptan succinate.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.

On Jul, 31, 2026

64 people who take Sumatriptan succinate and Mucinex together, and have interactions are studied.

Sumatriptan succinate and Mucinex drug interactions.

What are the common drug interactions of Sumatriptan Succinate and Mucinex, by gender? *:

female:

Epistaxis (bleed from the nose)
Essential tremor
Eye pain
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Fluid retention (an abnormal accumulation of fluid in the blood)
Flushing (the warm, red condition of human skin)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Glossodynia (a burning or painful sensation in the tongue)
Haematuria (presence of blood in urine)
Heart valve incompetence (heart's valves do not work correctly)

male:

Renal impairment (severely reduced kidney function)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Pain
Abdominal pain upper
Blood urine present
Chest pain
Coma (state of unconsciousness lasting more than six hours)
Drug ineffective
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)

What are the common drug interactions of Sumatriptan Succinate and Mucinex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Nausea (feeling of having an urge to vomit)

20-29:

Discomfort
Headache (pain in head)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Pneumonia
Respiratory disorder (respiratory disease)
Sinusitis (inflammation of sinus)
Streptococcal infection
Tension headache
Application site reaction
Blood urine present

30-39:

Gestational diabetes (diabetes in pregnancy)
Ketoacidosis (high concentrations of ketone bodies in blood)
Renal failure (kidney dysfunction)

40-49:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Glossodynia (a burning or painful sensation in the tongue)
Hypersensitivity
Ill-defined disorder
Insomnia (sleeplessness)
Nasopharyngitis (inflammation of the nasopharynx)
Pain in extremity
Pneumonia
Pruritus generalised (generalized itching)
Respiratory tract infection

50-59:

Diarrhoea
Renal impairment (severely reduced kidney function)
Abdominal pain upper
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased
Bone density decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Coma (state of unconsciousness lasting more than six hours)

60+:

Back pain
Headache (pain in head)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Blood creatinine increased
Bone density decreased
Chest discomfort
Chills (felling of cold)
Confusional state

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 29.69%
Immunodeficiency Common Variable: 19 people, 29.69%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 17.19%
Sleep Disorder: 6 people, 9.38%
Asthma: 4 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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