Sumatriptan succinate and Pyridium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sumatriptan succinate (sumatriptan succinate) and Pyridium (phenazopyridine hydrochloride). Common drug interactions include depression among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Sumatriptan succinate and Pyridium. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Sumatriptan succinate?

Sumatriptan succinate has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 9,731 Sumatriptan succinate users. Check the latest studies of Sumatriptan succinate.

What is Pyridium?

Pyridium has active ingredients of phenazopyridine hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 1,841 Pyridium users. Check the latest studies of Pyridium.



On Jul, 10, 2026

24 people who take Sumatriptan succinate and Pyridium together, and have interactions are studied.

Sumatriptan succinate and Pyridium drug interactions.

What are the common drug interactions of Sumatriptan Succinate and Pyridium, by gender? *:

female:

  1. Depression
  2. Drug hypersensitivity
  3. Intervertebral disc protrusion (spinal disc protrusion)
  4. Nerve injury
  5. Syncope (loss of consciousness with an inability to maintain postural tone)
  6. Blood pressure decreased
  7. Bradycardia (abnormally slow heart action)
  8. Foot fracture
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

male:

  1. Anxiety
  2. Bradycardia (abnormally slow heart action)
  3. Nausea (feeling of having an urge to vomit)
  4. Night sweats (sweating in night)
  5. Palpitations (feelings or sensations that your heart is pounding or racing)
  6. Renal failure (kidney dysfunction)
  7. Sinus bradycardia (an unusually slow heartbeat due to heart disease)
  8. Chest pain
  9. Chronic kidney disease
  10. Diarrhoea

What are the common drug interactions of Sumatriptan Succinate and Pyridium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  2. Cardiac disorder
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Ear infection
  5. Foot fracture
  6. Infected cyst
  7. Infusion site reaction
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Nasopharyngitis (inflammation of the nasopharynx)
  10. Nephrolithiasis (calculi in the kidneys)

50-59:

n/a

60+:

  1. Anxiety
  2. Bradycardia (abnormally slow heart action)
  3. Palpitations (feelings or sensations that your heart is pounding or racing)
  4. Sinus bradycardia (an unusually slow heartbeat due to heart disease)
  5. Chest pain
  6. Dizziness
  7. Dyspnoea (difficult or laboured respiration)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Headache (pain in head)
  10. Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 50.00%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 37.50%
  3. Pain: 2 people, 8.33%
  4. Immunodeficiency Common Variable: 2 people, 8.33%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.33%
  6. Depression: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Sumatriptan succinate and Pyridium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sumatriptan succinate and Pyridium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sumatriptan succinate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pyridium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sumatriptan succinate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pyridium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sumatriptan succinate and phenazopyridine hydrochloride (the active ingredients of Sumatriptan succinate and Pyridium, respectively), and Sumatriptan succinate and Pyridium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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