Sumatriptan and Migranal drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sumatriptan (sumatriptan succinate) and Migranal (dihydroergotamine mesylate). Common drug interactions include anxiety among females and appendicitis perforated among males.
The phase IV clinical study analyzes what interactions people have when they take Sumatriptan and Migranal. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.
What is Sumatriptan?
Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.
What is Migranal?
Migranal has active ingredients of dihydroergotamine mesylate. It is often used in migraine. eHealthMe is studying from 560 Migranal users. Check the latest studies of Migranal.
39 people who take Sumatriptan and Migranal together, and have interactions are studied.

What are the common drug interactions of Sumatriptan and Migranal, by gender? *:
female:
- Anxiety
- Fatigue (feeling of tiredness)
- Memory impairment
- Dizziness
- Abdominal discomfort
- Pain
- Nausea (feeling of having an urge to vomit)
- Post-traumatic stress disorder
- Drug ineffective
- Tremor (trembling or shaking movements in one or more parts of your body)
male:
- Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Gallbladder disorder
- Injury
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Pain
- Pancreatitis acute (sudden inflammation of pancreas)
- Rash
- Renal failure acute (rapid kidney dysfunction)
What are the common drug interactions of Sumatriptan and Migranal, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Hunger
- Somnolence (a state of near-sleep, a strong desire for sleep)
30-39:
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Pain
- Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Gallbladder disorder
- Injury
- Pancreatitis acute (sudden inflammation of pancreas)
- Renal failure acute (rapid kidney dysfunction)
- Anxiety
40-49:
- Ligament sprain (ligament stretched)
- Loss of consciousness
- Memory impairment
- Post-traumatic stress disorder
- Wrist fracture
- Therapeutic response unexpected
- Essential tremor
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Hypotension (abnormally low blood pressure)
- Orthostatic intolerance (development of symptoms when standing upright which are relieved when sitting back down again)
50-59:
- Suicidal ideation
- Dizziness
- Headache (pain in head)
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
60+:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 31 people, 79.49%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 29 people, 74.36%
- Birth Control: 4 people, 10.26%
- Pain: 3 people, 7.69%
- Nausea And Vomiting: 3 people, 7.69%
- Nausea (feeling of having an urge to vomit): 3 people, 7.69%
- Headache (pain in head): 3 people, 7.69%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.69%
- Perennial Allergy (airborne allergy): 2 people, 5.13%
- Hypersensitivity: 2 people, 5.13%
* Approximation only. Some reports may have incomplete information.
Do you take Sumatriptan and Migranal?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sumatriptan (18,159 reports)
- Migranal (560 reports)
Browse all drug interactions of Sumatriptan and Migranal:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sumatriptan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Migranal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sumatriptan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Migranal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on sumatriptan succinate and dihydroergotamine mesylate (the active ingredients of Sumatriptan and Migranal, respectively), and Sumatriptan and Migranal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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