Sumatriptan and Niaspan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sumatriptan (sumatriptan succinate) and Niaspan (niacin). Common drug interactions include flushing among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Sumatriptan and Niaspan. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

What is Niaspan?

Niaspan has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 45,453 Niaspan users. Check the latest studies of Niaspan.



On Jul, 08, 2026

18 people who take Sumatriptan and Niaspan together, and have interactions are studied.

Sumatriptan and Niaspan drug interactions.

What are the common drug interactions of Sumatriptan and Niaspan, by gender? *:

female:

  1. Flushing (the warm, red condition of human skin)
  2. Pruritus (severe itching of the skin)
  3. Erythema (redness of the skin)
  4. Skin burning sensation
  5. Pain
  6. Dizziness
  7. Dyspnoea (difficult or laboured respiration)
  8. Hypersensitivity
  9. Myalgia (muscle pain)
  10. Rash

male:

  1. Flushing (the warm, red condition of human skin)
  2. Headache (pain in head)
  3. General physical health deterioration (weak health status)
  4. Pain
  5. Quality of life decreased
  6. Renal failure (kidney dysfunction)
  7. Renal injury (kidney injury)
  8. Injury
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Anxiety

What are the common drug interactions of Sumatriptan and Niaspan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Erythema (redness of the skin)
  2. Flushing (the warm, red condition of human skin)
  3. Pruritus (severe itching of the skin)
  4. Skin burning sensation
  5. Dizziness
  6. Dyspnoea (difficult or laboured respiration)
  7. Pain
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

50-59:

  1. Flushing (the warm, red condition of human skin)
  2. Erythema (redness of the skin)
  3. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
  4. Psychotic disorder
  5. Skin burning sensation
  6. Chronic kidney disease
  7. Dizziness
  8. Feeling hot
  9. Nausea (feeling of having an urge to vomit)
  10. Oedema peripheral (superficial swelling)

60+:

  1. Headache (pain in head)
  2. Flushing (the warm, red condition of human skin)
  3. Dizziness
  4. Emotional disorder
  5. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  6. Fall
  7. Fatigue (feeling of tiredness)
  8. Head injury
  9. Iron deficiency anaemia
  10. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

What are the existing conditions these people have? *

  1. High Blood Pressure: 2 people, 11.11%
  2. Pain: 2 people, 11.11%
  3. High Density Lipoprotein Decreased: 2 people, 11.11%
  4. Headache (pain in head): 2 people, 11.11%
  5. Gout (uric acid crystals building up in the body): 1 person, 5.56%
  6. Blood Testosterone Increased: 1 person, 5.56%
  7. Bone Disorder: 1 person, 5.56%
  8. Cardiac Disorder: 1 person, 5.56%
  9. Diabetes: 1 person, 5.56%
  10. Erection Problems: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Sumatriptan and Niaspan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sumatriptan and Niaspan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sumatriptan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Niaspan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sumatriptan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Niaspan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sumatriptan succinate and niacin (the active ingredients of Sumatriptan and Niaspan, respectively), and Sumatriptan and Niaspan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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