Sumatriptan and Nuvaring drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sumatriptan (sumatriptan succinate) and Nuvaring (ethinyl estradiol; etonogestrel). Common drug interactions include depression among females.

The phase IV clinical study analyzes what interactions people have when they take Sumatriptan and Nuvaring. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

What is Nuvaring?

Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,730 Nuvaring users. Check the latest studies of Nuvaring.

On Aug, 02, 2026

50 people who take Sumatriptan and Nuvaring together, and have interactions are studied.

Sumatriptan and Nuvaring drug interactions.

What are the common drug interactions of Sumatriptan and Nuvaring, by gender? *:

female:

Depression
Anxiety
Haematocrit decreased
Haematoma (collection of blood outside the blood vessels)
Hypotension (abnormally low blood pressure)
Vaginal haemorrhage (vaginal bleeding)
Seroma (a tumour like collection of serum in the tissues)
Skin discolouration (change of skin colour)
Haemoglobin decreased
Heart rate increased

male:

n/a

What are the common drug interactions of Sumatriptan and Nuvaring, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)

20-29:

Urinary tract infection
Uterine haemorrhage (uterine bleeding)
Vaginal discharge
Vulvovaginal pain
Abdominal distension
Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Hypersensitivity
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Pyrexia (fever)

30-39:

Crying
Depression
Fatigue (feeling of tiredness)
Blood pressure increased
Cellulitis (infection under the skin)
Gastric bypass
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Intestinal obstruction
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Depression
Insomnia (sleeplessness)
Haematocrit decreased
Haematoma (collection of blood outside the blood vessels)
Hypotension (abnormally low blood pressure)
Vaginal haemorrhage (vaginal bleeding)
Seroma (a tumour like collection of serum in the tissues)
Skin discolouration (change of skin colour)
Haemoglobin decreased
Heart rate increased

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 28.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 20.00%
Drowsiness: 6 people, 12.00%
Thrombosis (formation of a blood clot inside a blood vessel): 4 people, 8.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Sumatriptan and Nuvaring?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously