Sumatriptan and Restoril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sumatriptan (sumatriptan succinate) and Restoril (temazepam). Common drug interactions include klebsiella infection among females and renal impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Sumatriptan and Restoril. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

What is Restoril?

Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.

On Jul, 10, 2026

27 people who take Sumatriptan and Restoril together, and have interactions are studied.

Sumatriptan and Restoril drug interactions.

What are the common drug interactions of Sumatriptan and Restoril, by gender? *:

female:

Klebsiella infection
Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
Leukocytosis (increased white blood cells)
Ligament rupture (tear in ligament)
Lung neoplasm malignant (cancer tumour of lung)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Neoplasm (tumour)
Anaemia (lack of blood)
Asthenia (weakness)
Drug ineffective

male:

Renal impairment (severely reduced kidney function)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chronic kidney disease
Dizziness
Drug ineffective
Hyperkalaemia (damage to or disease of the kidney)
Renal failure (kidney dysfunction)
Rib fracture
Sensory disturbance (sense disturbance)
Anxiety

What are the common drug interactions of Sumatriptan and Restoril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dizziness
Drug ineffective
Hunger
Sensory disturbance (sense disturbance)
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

Abdominal pain lower
Anaemia (lack of blood)
Bladder hypertrophy (bladder overgrowth- increase in cell size)
Cardiomyopathy (weakening of the heart muscle)
Chronic kidney disease
Cystitis (inflammation of the wall of the bladder)
Delirium (wild excitement)
Detrusor sphincter dyssynergia (lack of external sphincter relaxation during voluntary voiding)
Device related infection
Escherichia sepsis (bacterial infection by escherichia coli)

40-49:

Drug ineffective
Back pain
Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression)
General physical health deterioration (weak health status)
Pain
Suicidal ideation
Abnormal weight gain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bipolar disorder (mood disorder)
Blood cholesterol increased
Blood creatinine increased
Breast abscess
Breast cyst
Breast pain
C-reactive protein increased

60+:

Abdominal pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Haemolytic anaemia (anaemia due to haemolysis)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Joint injury
Nephrogenic anaemia (anaemia due to kidney disease)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Sleep Disorder: 6 people, 22.22%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 18.52%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 14.81%
Muscle Spasms (muscle contraction): 4 people, 14.81%
Stress And Anxiety: 3 people, 11.11%
Depression: 3 people, 11.11%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 11.11%
Granulocyte Count Decreased: 2 people, 7.41%
Breast Cancer Metastatic: 2 people, 7.41%
Discomfort: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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