Sumatriptan and Rinvoq drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sumatriptan (sumatriptan succinate) and Rinvoq (upadacitinib). Common drug interactions include surgery among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Sumatriptan and Rinvoq. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

What is Rinvoq?

Rinvoq has active ingredients of upadacitinib. eHealthMe is studying from 47,375 Rinvoq users. Check the latest studies of Rinvoq.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

42 people who take Sumatriptan and Rinvoq together, and have interactions are studied.

Sumatriptan and Rinvoq drug interactions.

What are the common drug interactions of Sumatriptan and Rinvoq, by gender? *:

female:

Surgery
Cartilage injury
Herpes zoster
Impaired fasting glucose
Joint injury
Ovarian cyst (fluid filled sac of the ovary)
Procedural pain
Anaemia (lack of blood)
Arthralgia (joint pain)
Urinary tract infection

male:

Arthralgia (joint pain)
Bacterial infection
Pain
Pruritus (severe itching of the skin)
Scrotal abscess (pus in scrotum)
Skin infection
Chills (felling of cold)
Drug ineffective
Hypoaesthesia (reduced sense of touch or sensation)
Inflammation

What are the common drug interactions of Sumatriptan and Rinvoq, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Back pain
Confusional state
Diarrhoea
Mobility decreased (ability to move is reduced)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Vomiting

30-39:

Abdominal pain
Chills (felling of cold)
Confusional state
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Feeling cold
Feeling hot
Headache (pain in head)
Infusion site pain
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)

40-49:

Cartilage injury
Herpes zoster
Impaired fasting glucose
Joint injury
Ovarian cyst (fluid filled sac of the ovary)
Procedural pain
Surgery
Arthralgia (joint pain)
Arthropathy
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

50-59:

Anaemia (lack of blood)
Adverse drug reaction
Cellulitis (infection under the skin)
Device dislocation
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
Lipoma (a growth of fatty tissue that slowly develops just under your skin)
Necrosis (the death of body tissue)
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
Sepsis (a severe blood infection that can lead to organ failure and death)

60+:

Cataract (clouding of the lens inside the eye)
Acute respiratory failure
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Adverse drug reaction
Asthma
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Influenza
Pneumonia
Adverse event
Headache (pain in head)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 25 people, 59.52%
Pain: 4 people, 9.52%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.52%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 4 people, 9.52%
High Blood Pressure: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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