Sumatriptan and Sennosides drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sumatriptan (sumatriptan succinate) and Sennosides (senna). Common drug interactions include blood pressure increased among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Sumatriptan and Sennosides. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

What is Sennosides?

Sennosides has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 8,247 Sennosides users. Check the latest studies of Sennosides.

On Jul, 17, 2026

49 people who take Sumatriptan and Sennosides together, and have interactions are studied.

Sumatriptan and Sennosides drug interactions.

What are the common drug interactions of Sumatriptan and Sennosides, by gender? *:

female:

Blood pressure increased
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Clostridium test positive
Conjunctivitis (pink eye)
Cystic fibrosis (disease of the secretary glands)
Death
Dehydration (dryness resulting from the removal of water)
Dermatitis allergic (inflammation of the skin due allergic reaction)
Headache (pain in head)

male:

Anxiety
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Skin ulcer
Cardiac failure congestive
Osteopenia (a condition where bone mineral density is lower than normal)
Abdominal distension
Asthenia (weakness)
Back pain
Blood creatinine increased
Bone density decreased

What are the common drug interactions of Sumatriptan and Sennosides, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Emergency care
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Suicidal ideation
Therapeutic response unexpected

20-29:

n/a

30-39:

Febrile neutropenia (fever with reduced white blood cells)
Pancreatitis acute (sudden inflammation of pancreas)

40-49:

Iron deficiency
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Skin ulcer
Diarrhoea
Nausea (feeling of having an urge to vomit)
Vomiting

50-59:

Anxiety
Depression
Dizziness
Fatigue (feeling of tiredness)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pain
Renal impairment (severely reduced kidney function)

60+:

Cardiac failure congestive
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Renal impairment (severely reduced kidney function)
Renal injury (kidney injury)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bacterial test positive
Blood creatinine increased
Bone density decreased

What are the existing conditions these people have? *

Pain: 11 people, 22.45%
Headache (pain in head): 9 people, 18.37%
Dyspnea (difficult or laboured breathing): 9 people, 18.37%
Nausea (feeling of having an urge to vomit): 8 people, 16.33%
Stress And Anxiety: 7 people, 14.29%
Nausea And Vomiting: 7 people, 14.29%
Multiple Myeloma (cancer of the plasma cells): 6 people, 12.24%
Cough: 6 people, 12.24%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 10.20%
Fever: 5 people, 10.20%

* Approximation only. Some reports may have incomplete information.

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