Sumatriptan and Zelnorm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sumatriptan (sumatriptan succinate) and Zelnorm (tegaserod maleate). Common drug interactions include drug ineffective among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Sumatriptan and Zelnorm. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.

What is Zelnorm?

Zelnorm has active ingredients of tegaserod maleate. eHealthMe is studying from 7,261 Zelnorm users. Check the latest studies of Zelnorm.

On Jul, 17, 2026

13 people who take Sumatriptan and Zelnorm together, and have interactions are studied.

Sumatriptan and Zelnorm drug interactions.

What are the common drug interactions of Sumatriptan and Zelnorm, by gender? *:

female:

Drug ineffective
Intervertebral disc protrusion (spinal disc protrusion)
Neuralgia (pain in one or more nerves)
Muscle spasms (muscle contraction)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Depressed mood
Gastrointestinal infection (infection of stomach and intestine)
Pain
Abnormal faeces (abnormal stool)
Anxiety

male:

Abdominal pain
Dehydration (dryness resulting from the removal of water)
Blood alkaline phosphatase increased
Blood bilirubin increased
Blood creatinine increased
Blood lactate dehydrogenase increased
Hepatic failure (liver failure)
Hepatitis (inflammation of the liver)
Hepatocellular damage (liver damage)
Pancreatitis (inflammation of pancreas)

What are the common drug interactions of Sumatriptan and Zelnorm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dry mouth
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Renal failure acute (rapid kidney dysfunction)
Vomiting
Alanine aminotransferase increased
Aspartate aminotransferase increased

50-59:

Blood pressure fluctuation
Dry eye (lack of adequate tears)
Heart rate decreased
Muscle spasms (muscle contraction)
Drug ineffective
Intervertebral disc protrusion (spinal disc protrusion)
Neuralgia (pain in one or more nerves)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)

60+:

Abnormal faeces (abnormal stool)
Change of bowel habit
Gastrointestinal motility disorder (abnormal intestinal contractions)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Painful defaecation
Rectal haemorrhage (bleeding from anus)

What are the existing conditions these people have? *

Insomnia (sleeplessness): 9 people, 69.23%
Impaired Gastric Emptying: 2 people, 15.38%
Headache (pain in head): 1 person, 7.69%
Constipation: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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