Sunitinib malate and Toprol-xl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sunitinib malate (sunitinib malate) and Toprol-xl (metoprolol succinate). Common drug interactions include cerebral ischaemia among females and renal failure acute among males.

The phase IV clinical study analyzes what interactions people have when they take Sunitinib malate and Toprol-xl. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Sunitinib malate?

Sunitinib malate has active ingredients of sunitinib malate. eHealthMe is studying from 9,160 Sunitinib malate users. Check the latest studies of Sunitinib malate.

What is Toprol-xl?

Toprol-xl has active ingredients of metoprolol succinate. It is often used in high blood pressure. eHealthMe is studying from 40,636 Toprol-xl users. Check the latest studies of Toprol-xl.

On Jul, 16, 2026

35 people who take Sunitinib malate and Toprol-xl together, and have interactions are studied.

Sunitinib malate and Toprol-xl drug interactions.

What are the common drug interactions of Sunitinib Malate and Toprol-Xl, by gender? *:

female:

Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Hypokalaemia (low potassium)
Left ventricular dysfunction
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Coronary artery stenosis (narrowing of coronary artery)
Diarrhoea
Ejection fraction decreased (systolic heart failure)
Microangiopathic haemolytic anaemia (anaemia due to inability of bone marrow to compensate the premature destruction of red blood cells)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Thrombocytopenia (decrease of platelets in blood)

male:

Renal failure acute (rapid kidney dysfunction)
Diarrhoea
Intussusception
Respiratory failure (inadequate gas exchange by the respiratory system)
Thrombocytopenia (decrease of platelets in blood)
Vomiting
Abdominal discomfort
Contusion (a type of hematoma of tissue in which capillaries)
Nausea (feeling of having an urge to vomit)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the common drug interactions of Sunitinib Malate and Toprol-Xl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hyperglycaemia (high blood sugar)
Infection

50-59:

Syncope (loss of consciousness with an inability to maintain postural tone)
Dehydration (dryness resulting from the removal of water)
Gastrointestinal necrosis (destruction of gastrointestinal organ)
Hypokalaemia (low potassium)
Hypotension (abnormally low blood pressure)
Hypovolaemia (a decreased volume of circulating blood in the body)
Intussusception
Left ventricular dysfunction
Renal failure acute (rapid kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

Diarrhoea
Thrombocytopenia (decrease of platelets in blood)
Hypotension (abnormally low blood pressure)
Localised oedema (fluid retention in a particular part of the body)
Mucosal inflammation (infection of mucous membrane)
Swollen tongue (swelling of tongue)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Pulmonary embolism (blockage of the main artery of the lung)
Body temperature decreased

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 15 people, 42.86%
Lung Cancer - Non-Small Cell (lung cancer): 6 people, 17.14%
Insomnia (sleeplessness): 4 people, 11.43%
Diabetes: 4 people, 11.43%
Bladder Transitional Cell Carcinoma (types of bladder cancer): 4 people, 11.43%
Ventricular Extrasystoles (premature cardiac contraction): 3 people, 8.57%
Seasonal Allergy (allergic condition due to certain season): 3 people, 8.57%
Prostate Cancer: 3 people, 8.57%
Nausea (feeling of having an urge to vomit): 3 people, 8.57%
Metastases To Bone (cancer spreads to bone): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

Do you take Sunitinib malate and Toprol-xl?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously