Suprane and Diprivan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Suprane (desflurane) and Diprivan (propofol). Common drug interactions include hypokalaemia among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Suprane and Diprivan. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.

What is Suprane?

Suprane has active ingredients of desflurane. eHealthMe is studying from 1,000 Suprane users. Check the latest studies of Suprane.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,496 Diprivan users. Check the latest studies of Diprivan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

97 people who take Suprane and Diprivan together, and have interactions are studied.

What are the common drug interactions of Suprane and Diprivan, by gender? *:

female:

Hypokalaemia (low potassium)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Pyrexia (fever)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Hypoxia (low oxygen in tissues)
Ageusia (loss of taste functions of the tongue)
Anosmia (partial or complete loss of the sense of smell)
Blood creatine phosphokinase increased
Blood potassium decreased

male:

Cardiac arrest
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Septic shock (shock due to blood infection)
Weight decreased
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Acute respiratory distress syndrome
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood creatine phosphokinase increased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

What are the common drug interactions of Suprane and Diprivan, by age (0-1 to 60+)? *:

0-1:

Alanine aminotransferase increased
Blood creatine phosphokinase increased
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Coagulation factor decreased (less clotting substance in blood)
Cytolytic hepatitis (dissolution or destruction of a liver cell)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Haematemesis (vomiting of blood)
Hypertension (high blood pressure)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Pyrexia (fever)

2-9:

n/a

10-19:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Alveolitis (inflammation in the socket of a tooth)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cough
Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hypoxia (low oxygen in tissues)
Respiratory distress (difficulty in breathing)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Blood pressure decreased

20-29:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Hypotension (abnormally low blood pressure)
Angioedema (rapid swelling of the dermis)
Bradycardia (abnormally slow heart action)
Cardiac arrest
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)

30-39:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Hepatitis (inflammation of the liver)
Asthenia (weakness)
Blood bilirubin increased
Eosinophil count increased
Ileus (a painful obstruction of the ileum or other part of the intestine)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Nausea (feeling of having an urge to vomit)
Urine discolouration
Urticaria (rash of round, red welts on the skin that itch intensely)

40-49:

Renal failure (kidney dysfunction)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Hepatitis (inflammation of the liver)
Transaminases increased
Cardiac arrest
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Erythema (redness of the skin)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Disseminated intravascular coagulation (systemic activation of blood coagulation)

50-59:

Cardiac arrest
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Haemangioma of liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Anaesthetic complication
Blood pressure increased
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Postictal paralysis
Restlessness (not able to rest)

60+:

Cytolytic hepatitis (dissolution or destruction of a liver cell)
Hypotension (abnormally low blood pressure)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Electrocardiogram qt prolonged
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)

What are the existing conditions these people have? *

Anaesthesia: 30 people, 30.93%
General Anaesthesia: 19 people, 19.59%
Pain: 9 people, 9.28%
High Blood Pressure: 5 people, 5.15%

* Approximation only. Some reports may have incomplete information.

Do you take Suprane and Diprivan?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously