Sustiva and Cefuroxime drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sustiva (efavirenz) and Cefuroxime (cefuroxime sodium). Common drug interactions include dry skin among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Sustiva and Cefuroxime. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Sustiva?

Sustiva has active ingredients of efavirenz. It is often used in hiv infection. eHealthMe is studying from 11,040 Sustiva users. Check the latest studies of Sustiva.

What is Cefuroxime?

Cefuroxime has active ingredients of cefuroxime sodium. It is often used in sinusitis. eHealthMe is studying from 12,999 Cefuroxime users. Check the latest studies of Cefuroxime.

On Jul, 20, 2026

32 people who take Sustiva and Cefuroxime together, and have interactions are studied.

Sustiva and Cefuroxime drug interactions.

What are the common drug interactions of Sustiva and Cefuroxime, by gender? *:

female:

Dry skin
Fatigue (feeling of tiredness)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Gait disturbance
Gingival pain (gum pain)
Hospitalisation
Infectious peritonitis (inflammation of the peritoneum, typically caused by bacterial infection)
Inflammatory bowel disease
Live birth
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Intestinal perforation (complete penetration of the wall of the intestine)
Intraventricular haemorrhage (intraventricular bleeding)
Neonatal respiratory distress syndrome (a serious medical condition where a newborn baby's lungs cannot provide their body with enough oxygen)
Osteoporosis (bones weak and more likely to break)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Premature baby
Retinopathy of prematurity (retina damage in premature)
Strabismus (a disorder in which the two eyes do not line up in the same direction)

What are the common drug interactions of Sustiva and Cefuroxime, by age (0-1 to 60+)? *:

0-1:

Cerebral palsy
Hydrocephalus (water on the brain)
Intestinal perforation (complete penetration of the wall of the intestine)
Intraventricular haemorrhage (intraventricular bleeding)
Respiratory distress (difficulty in breathing)
Retinopathy of prematurity (retina damage in premature)
Strabismus (a disorder in which the two eyes do not line up in the same direction)
Bronchopulmonary dysplasia (chronic lung disorder in infants - enlargement of an organ or tissue by the proliferation of cells of an abnormal type)
Developmental delay
Infectious peritonitis (inflammation of the peritoneum, typically caused by bacterial infection)

2-9:

n/a

10-19:

n/a

20-29:

Premature rupture of membranes
Twin pregnancy (two babies in uterus)
Premature labour
Arthralgia (joint pain)
Blood cholesterol increased
Blood triglycerides increased
Chapped lips (cracking, fissuring, and peeling of the skin f lip)
Cheilitis (infection of lips)
Chest pain
Colitis ulcerative (inflammation of colon with ulcer)

30-39:

Tooth loss
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Bone density decreased
Chronic kidney disease
Depression
Emotional distress
Gait disturbance
Oedema peripheral (superficial swelling)

40-49:

Calculus ureteric (stone in ureter)
Hydronephrosis (water inside the kidney)
Nephrolithiasis (calculi in the kidneys)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Chronic kidney disease
Bone density decreased
Osteoporosis (bones weak and more likely to break)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Bone density decreased
Bone loss
Hand fracture
Tooth loss
Depression
Multiple fractures

60+:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Premature baby
Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Back pain
Blood creatinine increased
Bronchopulmonary dysplasia (chronic lung disorder in infants - enlargement of an organ or tissue by the proliferation of cells of an abnormal type)
Cardiac arrest
Chronic kidney disease

What are the existing conditions these people have? *

Hiv Infection: 24 people, 75.00%
Urinary Tract Infection: 8 people, 25.00%
Pain: 6 people, 18.75%
Aphthous Stomatitis (mouth ulcer): 5 people, 15.62%
Anaemia (lack of blood): 5 people, 15.62%
Maternal Therapy To Enhance Foetal Lung Maturity: 3 people, 9.38%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 6.25%
Iron Deficiency Anaemia: 2 people, 6.25%
High Blood Cholesterol: 2 people, 6.25%
Headache (pain in head): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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