Sustiva and Temaz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sustiva (efavirenz) and Temaz (temazepam). Common drug interactions include bone density decreased among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Sustiva and Temaz. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Sustiva?

Sustiva has active ingredients of efavirenz. It is often used in hiv infection. eHealthMe is studying from 11,040 Sustiva users. Check the latest studies of Sustiva.

What is Temaz?

Temaz has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 42,293 Temaz users. Check the latest studies of Temaz.

On Jul, 29, 2026

47 people who take Sustiva and Temaz together, and have interactions are studied.

What are the common drug interactions of Sustiva and Temaz, by gender? *:

female:

Bone density decreased
Decreased activity
Dizziness
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Fatigue (feeling of tiredness)
Feeling jittery
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Hip fracture
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Malaise (a feeling of general discomfort or uneasiness)

male:

Anxiety
Emotional distress
Depression
Renal impairment (severely reduced kidney function)
Blood creatinine increased
Decreased activity
Mobility decreased (ability to move is reduced)
Osteopenia (a condition where bone mineral density is lower than normal)
Quality of life decreased
Diarrhoea

What are the common drug interactions of Sustiva and Temaz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Emotional distress
Pain
Anxiety
Bone density decreased
Renal failure (kidney dysfunction)
Chronic kidney disease
Fracture
Osteoporosis (bones weak and more likely to break)
Decreased activity
Depression

40-49:

Diarrhoea
Fatigue (feeling of tiredness)
Pain
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood bilirubin increased
Chronic kidney disease
Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture

50-59:

Chronic kidney disease
Anxiety
Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Pain
Osteopenia (a condition where bone mineral density is lower than normal)
Bone density decreased
Renal impairment (severely reduced kidney function)
Compression fracture (fracture due to pressure caused by injury)
Gait disturbance

60+:

Anxiety
Emotional distress
Hypertension (high blood pressure)
Bone density decreased
Bone loss
Cardiac failure congestive
Cardiomyopathy alcoholic
Decreased activity
Fatigue (feeling of tiredness)
Multiple fractures

What are the existing conditions these people have? *

Hiv Infection: 29 people, 61.70%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 21.28%
Pain: 10 people, 21.28%
Bacterial Infection: 9 people, 19.15%
Stress And Anxiety: 8 people, 17.02%
Nausea (feeling of having an urge to vomit): 7 people, 14.89%
Depression: 6 people, 12.77%
Hypersensitivity: 6 people, 12.77%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 5 people, 10.64%
Inflammation: 5 people, 10.64%

* Approximation only. Some reports may have incomplete information.

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