Sutent and Hydrocodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sutent (sunitinib malate) and Hydrocodone (hydrocodone bitartrate; ibuprofen). Common drug interactions include cerebellar infarction among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Sutent and Hydrocodone. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Sutent?

Sutent has active ingredients of sunitinib malate. It is often used in renal cell carcinoma. eHealthMe is studying from 44,554 Sutent users. Check the latest studies of Sutent.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.



On Jul, 09, 2026

22 people who take Sutent and Hydrocodone together, and have interactions are studied.

Sutent and Hydrocodone drug interactions.

What are the common drug interactions of Sutent and Hydrocodone, by gender? *:

female:

  1. Cerebellar infarction (impaired blood circulation to cerebellum)
  2. Diarrhoea
  3. Fatigue (feeling of tiredness)
  4. Abdominal pain
  5. Anxiety
  6. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  7. Confusional state
  8. Dehydration (dryness resulting from the removal of water)
  9. Dermatitis allergic (inflammation of the skin due allergic reaction)
  10. Drug intolerance (drug sensitivity)

male:

  1. Death
  2. Dehydration (dryness resulting from the removal of water)
  3. Cataract (clouding of the lens inside the eye)
  4. Constipation
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  6. Diarrhoea
  7. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  8. Disseminated intravascular coagulation (systemic activation of blood coagulation)
  9. Haematocrit decreased
  10. Hepatic failure (liver failure)

What are the common drug interactions of Sutent and Hydrocodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Confusional state
  2. Anaemia macrocytic (a macrocytic class of anaemia)
  3. Blood lactate dehydrogenase increased
  4. Chills (felling of cold)
  5. Fatigue (feeling of tiredness)
  6. Hypotension (abnormally low blood pressure)
  7. Localised infection (infection at the single location)
  8. Myalgia (muscle pain)
  9. Neuralgia (pain in one or more nerves)
  10. Pyrexia (fever)

60+:

  1. Cerebellar infarction (impaired blood circulation to cerebellum)
  2. Dehydration (dryness resulting from the removal of water)
  3. Fatigue (feeling of tiredness)
  4. Oral mucosal blistering (mouth ulcer)
  5. Oropharyngeal blistering (blister of oropharynx)
  6. Rash
  7. Skin exfoliation (removal of the oldest dead skin cells)
  8. Stomatitis (inflammation of mucous membrane of mouth)
  9. Tenderness (pain or discomfort when an affected area is touched)
  10. Thermal burn (burn by heat)

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 7 people, 31.82%
  2. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 4 people, 18.18%
  3. Prostate Cancer: 2 people, 9.09%
  4. Pain: 2 people, 9.09%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 9.09%
  6. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 9.09%
  7. Depression: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Sutent and Hydrocodone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sutent and Hydrocodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sutent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydrocodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sutent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrocodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sunitinib malate and hydrocodone bitartrate; ibuprofen (the active ingredients of Sutent and Hydrocodone, respectively), and Sutent and Hydrocodone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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