Symbicort and Rapaflo drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Symbicort (budesonide; formoterol fumarate dihydrate) and Rapaflo (silodosin). Common drug interactions include fibromyalgia among females and wheezing among males.
The phase IV clinical study analyzes what interactions people have when they take Symbicort and Rapaflo. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.
What is Symbicort?
Symbicort has active ingredients of budesonide; formoterol fumarate dihydrate. It is often used in asthma. eHealthMe is studying from 114,792 Symbicort users. Check the latest studies of Symbicort.
What is Rapaflo?
Rapaflo has active ingredients of silodosin. It is often used in prostate examination abnormal. eHealthMe is studying from 3,929 Rapaflo users. Check the latest studies of Rapaflo.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
73 people who take Symbicort and Rapaflo together, and have interactions are studied.

What are the common drug interactions of Symbicort and Rapaflo, by gender? *:
female:
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Headache (pain in head)
- Infection
- Nephrogenic anaemia (anaemia due to kidney disease)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Psoriasis (immune-mediated disease that affects the skin)
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Swelling face
- Tooth abscess (pus formation in tooth)
male:
- Wheezing (a high-pitched whistling sound made while you breath)
- Dyspnoea (difficult or laboured respiration)
- Balance disorder
- Hospitalisation
- Anaemia (lack of blood)
- Nausea (feeling of having an urge to vomit)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Weight decreased
- Blindness
What are the common drug interactions of Symbicort and Rapaflo, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Dizziness
- Dysstasia (difficulty in standing)
- Faecal incontinence (a lack of control over passing stool)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Visual impairment
40-49:
- Angina pectoris (chest pain due to ischemia of the heart muscle)
50-59:
- Arthralgia (joint pain)
- Back pain
- Blood cholesterol increased
- Bone density decreased
- Deafness
- Death
- Depression
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Erectile dysfunction
60+:
- Wheezing (a high-pitched whistling sound made while you breath)
- Dyspnoea (difficult or laboured respiration)
- Balance disorder
- Fatigue (feeling of tiredness)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Anaemia (lack of blood)
- Blindness
- Optic ischaemic neuropathy (optic nerve damage due to lack of blood supply)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Nasopharyngitis (inflammation of the nasopharynx)
What are the existing conditions these people have? *
- High Blood Cholesterol: 11 people, 15.07%
- Pain: 8 people, 10.96%
- Immunodeficiency Common Variable: 8 people, 10.96%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 9.59%
- Primary Immunodeficiency Syndrome: 6 people, 8.22%
- High Blood Pressure: 6 people, 8.22%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 8.22%
- Primary Myelofibrosis (primary disorder of the bone marrow): 5 people, 6.85%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 5.48%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 5.48%
* Approximation only. Some reports may have incomplete information.
Do you take Symbicort and Rapaflo?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Symbicort and Rapaflo:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Symbicort:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rapaflo:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Symbicort and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rapaflo and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on budesonide; formoterol fumarate dihydrate and silodosin (the active ingredients of Symbicort and Rapaflo, respectively), and Symbicort and Rapaflo (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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