Symproic and Humalog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Symproic (naldemedine tosylate) and Humalog (insulin lispro recombinant). Common drug interactions include cholecystitis among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Symproic and Humalog. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Symproic?

Symproic has active ingredients of naldemedine tosylate. eHealthMe is studying from 1,487 Symproic users. Check the latest studies of Symproic.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

On Aug, 08, 2026

16 people who take Symproic and Humalog together, and have interactions are studied.

What are the common drug interactions of Symproic and Humalog, by gender? *:

female:

Cholecystitis (infection of gallbladder)

male:

Constipation
Diarrhoea
Delirium (wild excitement)
Depressed level of consciousness
Dyspnoea (difficult or laboured respiration)
Epistaxis (bleed from the nose)
Erythema (redness of the skin)
Haemoglobin decreased
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Malignant neoplasm progression (cancer tumour came back)

What are the common drug interactions of Symproic and Humalog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain upper
Altered state of consciousness (altered state of mind)
Constipation
Delirium (wild excitement)
Diarrhoea
Mouth haemorrhage (bleeding from mouth)
Pain
Somnolence (a state of near-sleep, a strong desire for sleep)
Nasopharyngitis (inflammation of the nasopharynx)
Pyrexia (fever)

40-49:

n/a

50-59:

n/a

60+:

Anaemia (lack of blood)
Back pain
Depressed level of consciousness
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)
Epistaxis (bleed from the nose)
Erythema (redness of the skin)
Haemoglobin decreased
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

What are the existing conditions these people have? *

Hereditary Angioedema (recurrent episodes of severe swelling): 7 people, 43.75%
Stable Angina (a constant chest pain): 3 people, 18.75%
Blood Catecholamines Increased: 3 people, 18.75%
Lung Cancer - Non-Small Cell (lung cancer): 2 people, 12.50%
Stomatitis (inflammation of mucous membrane of mouth): 1 person, 6.25%
Renal Cell Carcinoma (a kidney cancer): 1 person, 6.25%
Palmar-Plantar Erythrodysaesthesia Syndrome (hand-foot syndrome): 1 person, 6.25%
Metastases To Bone (cancer spreads to bone): 1 person, 6.25%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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