Synribo and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Synribo (omacetaxine mepesuccinate) and Compazine (prochlorperazine maleate). Common drug interactions include hospitalisation among females and injection site erythema among males.

The phase IV clinical study analyzes what interactions people have when they take Synribo and Compazine. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Synribo?

Synribo has active ingredients of omacetaxine mepesuccinate. eHealthMe is studying from 799 Synribo users. Check the latest studies of Synribo.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

On Jul, 26, 2026

31 people who take Synribo and Compazine together, and have interactions are studied.

Synribo and Compazine drug interactions.

What are the common drug interactions of Synribo and Compazine, by gender? *:

female:

Hospitalisation
Platelet count increased
Asthma
Cough
Nasopharyngitis (inflammation of the nasopharynx)
Asthenia (weakness)
Hallucination (an experience involving the perception of something not present)
Urinary tract infection
Wrist fracture
Bacterial infection

male:

Injection site erythema (redness at injection site)
Asthenia (weakness)
Abdominal pain upper
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Intestinal haemorrhage (bleeding from intestine)
Loss of consciousness
Swelling
Drug ineffective
White blood cell count increased

What are the common drug interactions of Synribo and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug ineffective
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Injection site erythema (redness at injection site)
Intestinal haemorrhage (bleeding from intestine)
White blood cell count increased

30-39:

Injection site erythema (redness at injection site)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Intestinal haemorrhage (bleeding from intestine)
Drug ineffective
White blood cell count increased
Haemoglobin decreased

40-49:

Bone pain
Arthralgia (joint pain)
Blood glucose increased
Discomfort
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Irritability
Malaise (a feeling of general discomfort or uneasiness)
Mobility decreased (ability to move is reduced)
Pain
Splenomegaly (enlargement of spleen)

50-59:

White blood cell count decreased
Blood calcium decreased
Blood potassium increased
Haematocrit decreased
Haemoglobin decreased
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Hyperkalaemia (damage to or disease of the kidney)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)

60+:

Asthenia (weakness)
Abdominal distension
Back pain
Blood glucose decreased
Blood glucose increased
Burning sensation
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Epistaxis (bleed from the nose)
Feeling cold

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 29 people, 93.55%
Nausea (feeling of having an urge to vomit): 6 people, 19.35%
Pain: 4 people, 12.90%
Diabetes: 3 people, 9.68%
Stress And Anxiety: 2 people, 6.45%
Dyspnea (difficult or laboured breathing): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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