Tacrolimus and Aloe drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tacrolimus (tacrolimus) and Aloe (aloe). Common drug interactions include pruritus among females and food interaction among males.

The phase IV clinical study analyzes what interactions people have when they take Tacrolimus and Aloe. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Aloe?

Aloe has active ingredients of aloe. eHealthMe is studying from 2,128 Aloe users. Check the latest studies of Aloe.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

19 people who take Tacrolimus and Aloe together, and have interactions are studied.

What are the common drug interactions of Tacrolimus and Aloe, by gender? *:

female:

Pruritus (severe itching of the skin)
Allergy to arthropod sting
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Contusion (a type of hematoma of tissue in which capillaries)
Discomfort
Dry mouth
Dysgeusia (disorder of the sense of taste)
Dysphagia (a condition in which swallowing is difficult or painful)
Erythema (redness of the skin)
Headache (pain in head)

male:

Food interaction
Immunosuppressant drug level decreased
Rash pruritic (redness with itching)
Abdominal pain upper
Blood glucose increased
Constipation
Headache (pain in head)
Hypertension (high blood pressure)
Myalgia (muscle pain)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

What are the common drug interactions of Tacrolimus and Aloe, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chills (felling of cold)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Feeling hot
Inflammation
Insomnia (sleeplessness)
Neuralgia (pain in one or more nerves)
Pruritus (severe itching of the skin)
Skin exfoliation (removal of the oldest dead skin cells)

30-39:

n/a

40-49:

Food interaction
Immunosuppressant drug level decreased

50-59:

Headache (pain in head)
Allergy to arthropod sting
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Contusion (a type of hematoma of tissue in which capillaries)
Discomfort
Dry mouth
Dysgeusia (disorder of the sense of taste)
Dysphagia (a condition in which swallowing is difficult or painful)
Erythema (redness of the skin)
Muscle tightness

60+:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Initial insomnia (feeling of inadequate or poor-quality sleep)
Arthralgia (joint pain)
Back pain
Gastrointestinal pain
Injection site bruising
Injection site pruritus (severe itching at injection site)
Injection site swelling
Oral herpes (viral infection of mouth)
Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 7 people, 36.84%
Pemphigoid (tense blisters on the skin): 6 people, 31.58%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 31.58%
Iridocyclitis (inflammation of the iris and ciliary body of the eye): 6 people, 31.58%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 1 person, 5.26%
Itching: 1 person, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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