Tacrolimus and Dipyrone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tacrolimus (tacrolimus) and Dipyrone (metamizole). Common drug interactions include respiratory failure among females and urinary fistula among males.

The phase IV clinical study analyzes what interactions people have when they take Tacrolimus and Dipyrone. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Dipyrone?

Dipyrone has active ingredients of metamizole. eHealthMe is studying from 1,876 Dipyrone users. Check the latest studies of Dipyrone.

On Jul, 29, 2026

14 people who take Tacrolimus and Dipyrone together, and have interactions are studied.

Tacrolimus and Dipyrone drug interactions.

What are the common drug interactions of Tacrolimus and Dipyrone, by gender? *:

female:

Respiratory failure (inadequate gas exchange by the respiratory system)
Respiratory syncytial virus infection (viral disease of respiratory system)
Secretion discharge
Septic shock (shock due to blood infection)
Tachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased)
Visual acuity reduced (reduced clearness of vision)
Weight increased
Abortion induced (medically referred abortion)
Death
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

male:

Urinary fistula
Cough
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Epistaxis (bleed from the nose)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Mydriasis (a dilation of the pupil)
Neurological symptom (symptoms of nervous system disease)
Oxygen saturation decreased
Pain

What are the common drug interactions of Tacrolimus and Dipyrone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Neurogenic shock (insufficient blood flow throughout the body due to injury in spinal cord)
Pyrexia (fever)
Renal tubular necrosis (death of kidney tubules)
Tinnitus (a ringing in the ears)
Vasculitis (inflammation of a blood vessel or blood vessels)
Visceral congestion (blocking of internal organs of the body)
Visual acuity reduced (reduced clearness of vision)
Visual impairment
Bradycardia (abnormally slow heart action)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

10-19:

n/a

20-29:

Abdominal pain
Back pain
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Butterfly rash
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chest pain
Confusional state
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)

30-39:

Urinary fistula

40-49:

Hepatic artery stenosis (the abnormal narrowing of a hepatic artery)
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Neutropenia (an abnormally low number of neutrophils)

50-59:

n/a

60+:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Cough
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dyspnoea (difficult or laboured respiration)
Epstein-barr virus infection
Gait disturbance
Gamma-glutamyltransferase increased
Gastrointestinal disorder (functional problems of gastrointestinal tract)

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 35.71%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 14.29%
Pain: 2 people, 14.29%
Kidney Transplant Rejection: 2 people, 14.29%
Embolism Venous (embolus may pass into the arterial system): 2 people, 14.29%
Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 1 person, 7.14%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 7.14%
Nausea (feeling of having an urge to vomit): 1 person, 7.14%
Kidney Stones: 1 person, 7.14%
High Blood Cholesterol: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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