Tacrolimus and Exforge drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tacrolimus (tacrolimus) and Exforge (amlodipine besylate; valsartan). Common drug interactions include blood creatinine increased among females and rash among males.

The phase IV clinical study analyzes what interactions people have when they take Tacrolimus and Exforge. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

On Jul, 12, 2026

19 people who take Tacrolimus and Exforge together, and have interactions are studied.

Tacrolimus and Exforge drug interactions.

What are the common drug interactions of Tacrolimus and Exforge, by gender? *:

female:

Blood creatinine increased
Hyperglycaemia (high blood sugar)
Depression
Blood glucose increased
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Vomiting
Arthralgia (joint pain)
Blood pressure decreased
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)

male:

Rash
Upper respiratory tract infection
Pain in extremity
Peripheral swelling
Dizziness
Neuroendocrine tumour (a tumour that forms from cells that release hormones into the blood in response to a signal from the nervous system)
Psoriasis (immune-mediated disease that affects the skin)
Rectal neoplasm (tumour of rectum)
Tooth fracture
Tooth infection

What are the common drug interactions of Tacrolimus and Exforge, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Discomfort
Hypertensive crisis
Ophthalmoplegia (a paralysis or weakness of one or more of the muscles that control eye movement)
Renal failure (kidney dysfunction)
Vision blurred

40-49:

Haemoglobin decreased
Lymphocyte count decreased
Aspartate aminotransferase decreased
Blood glucose increased
Chest discomfort
High density lipoprotein decreased
Kidney transplant rejection
Pain in extremity
Peripheral swelling
Upper respiratory tract infection

50-59:

Blood creatinine increased
Hyperglycaemia (high blood sugar)
Acute respiratory distress syndrome

60+:

Rash
Depression
Upper respiratory tract infection
Arthralgia (joint pain)
Blood pressure decreased
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Decreased appetite
Delirium (wild excitement)
Diarrhoea
Drug level increased

What are the existing conditions these people have? *

High Blood Pressure: 15 people, 78.95%
Type 2 Diabetes: 5 people, 26.32%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 2 people, 10.53%
High Blood Cholesterol: 2 people, 10.53%
Itching: 2 people, 10.53%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 2 people, 10.53%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 10.53%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 10.53%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.53%
Cough: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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