Tacrolimus and Timolol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tacrolimus (tacrolimus) and Timolol (timolol). Common drug interactions include dermatitis atopic among females and mania among males.

The phase IV clinical study analyzes what interactions people have when they take Tacrolimus and Timolol. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Timolol?

Timolol has active ingredients of timolol. It is often used in glaucoma. eHealthMe is studying from 9,142 Timolol users. Check the latest studies of Timolol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

53 people who take Tacrolimus and Timolol together, and have interactions are studied.

Tacrolimus and Timolol drug interactions.

What are the common drug interactions of Tacrolimus and Timolol, by gender? *:

female:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Discomfort
Infection
Rash
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Blood creatinine increased
Gait disturbance
Mobility decreased (ability to move is reduced)

male:

Mania (a state of abnormally elevated or irritable mood)
Drug level increased
Aggression
Belligerence (aggressive or warlike behaviour)
Chronic kidney disease
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug intolerance (drug sensitivity)
Flight of ideas
Grandiosity (an unrealistic sense of superiority)
Impulsive behaviour

What are the common drug interactions of Tacrolimus and Timolol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug intolerance (drug sensitivity)
Arthralgia (joint pain)
Back pain
Osteonecrosis (death of bone)
Osteoporosis (bones weak and more likely to break)

20-29:

Diarrhoea
Immunosuppression

30-39:

n/a

40-49:

Chronic kidney disease
Anxiety
Depression
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Nephropathy (damage to or disease of a kidney)
Renal failure (kidney dysfunction)
Drug ineffective
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

50-59:

Blood creatine increased
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Blood creatinine increased
Gait disturbance
Mobility decreased (ability to move is reduced)
Muscle spasms (muscle contraction)
Pain in extremity
Cardiac valve disease (heart valve disease)

60+:

Mania (a state of abnormally elevated or irritable mood)
Drug level increased
Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
Pain of skin
Papule
Rash pruritic (redness with itching)
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Seborrhoeic keratosis (noncancerous (benign) skin growths that some people develop as they age. they often appear on the back or chest)
Vision blurred
Renal disorder (kidney disease)

What are the existing conditions these people have? *

Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 9 people, 16.98%
High Blood Pressure: 7 people, 13.21%
Pneumonia: 5 people, 9.43%
High Blood Cholesterol: 5 people, 9.43%
Rosacea (a skin condition that causes facial redness): 3 people, 5.66%
Pain: 3 people, 5.66%
Lichen Sclerosus (a skin disorder that causes the skin to become thin, whitened, wrinkled, and can cause itching and pain): 3 people, 5.66%
Keratitis (eye's cornea, the front part of the eye, becomes inflamed): 3 people, 5.66%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.66%
Dyshidrotic Eczema (skin condition in which blisters develop on the soles of your feet and/or the palms of hands): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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