Tacrolimus and Tradjenta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tacrolimus (tacrolimus) and Tradjenta (linagliptin). Common drug interactions include diarrhoea among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Tacrolimus and Tradjenta. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.
What is Tacrolimus?
Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.
What is Tradjenta?
Tradjenta has active ingredients of linagliptin. It is often used in diabetes. eHealthMe is studying from 9,987 Tradjenta users. Check the latest studies of Tradjenta.
47 people who take Tacrolimus and Tradjenta together, and have interactions are studied.

What are the common drug interactions of Tacrolimus and Tradjenta, by gender? *:
female:
- Diarrhoea
- Spinal fracture (fracture in one of vertebrae)
- Complications of transplanted liver
- Memory impairment
- Pyrexia (fever)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Vomiting
- Cellulitis (infection under the skin)
- Neoplasm malignant (cancer tumour)
- Abdominal pain lower
male:
- Death
- Diarrhoea
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- White blood cell count decreased
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Fall
- Asthenia (weakness)
- Blood cholesterol increased
- Blood glucose increased
What are the common drug interactions of Tacrolimus and Tradjenta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Blood cholesterol increased
- Toothache (tooth pain)
- Tooth disorder (tooth disease)
50-59:
- Chronic kidney disease
- Complications of transplanted liver
- Memory impairment
- Pyrexia (fever)
- Renal failure (kidney dysfunction)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Vomiting
- Cellulitis (infection under the skin)
- Abdominal pain lower
- Diarrhoea
60+:
- Death
- Diarrhoea
- Hypertension (high blood pressure)
- Malignant neoplasm progression (cancer tumour came back)
- Memory impairment
- Oedema (fluid collection in tissue)
- Respiratory syncytial virus infection (viral disease of respiratory system)
- Skin ulcer
- Abdominal discomfort
- Adverse event
What are the existing conditions these people have? *
- Pain: 4 people, 8.51%
* Approximation only. Some reports may have incomplete information.
Do you take Tacrolimus and Tradjenta?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Tacrolimus (116,160 reports)
- Tradjenta (9,987 reports)
Browse all drug interactions of Tacrolimus and Tradjenta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tacrolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tradjenta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tacrolimus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tradjenta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on tacrolimus and linagliptin (the active ingredients of Tacrolimus and Tradjenta, respectively), and Tacrolimus and Tradjenta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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