Tacrolimus and Ultomiris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tacrolimus (tacrolimus) and Ultomiris (ravulizumab-cwvz). Common drug interactions include pseudomembranous colitis among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Tacrolimus and Ultomiris. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

What is Ultomiris?

Ultomiris has active ingredients of ravulizumab-cwvz. eHealthMe is studying from 5,775 Ultomiris users. Check the latest studies of Ultomiris.

On Jul, 08, 2026

28 people who take Tacrolimus and Ultomiris together, and have interactions are studied.

Tacrolimus and Ultomiris drug interactions.

What are the common drug interactions of Tacrolimus and Ultomiris, by gender? *:

female:

Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
Platelet count decreased
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Hip arthroplasty
Nausea (feeling of having an urge to vomit)
Peripheral swelling
Pyrexia (fever)
Urinary tract infection
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)

male:

Headache (pain in head)
Fatigue (feeling of tiredness)
Visual impairment
Renal impairment (severely reduced kidney function)
Weight decreased
Arthralgia (joint pain)
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Balance disorder
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

What are the common drug interactions of Tacrolimus and Ultomiris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Ascites (accumulation of fluid in the abdominal cavity)
Haematoma (collection of blood outside the blood vessels)
Haemoglobin decreased
Hypotension (abnormally low blood pressure)
Polyuria (production of too much dilute urine)
Renal cell carcinoma (a kidney cancer)
Renal impairment (severely reduced kidney function)
Anaemia (lack of blood)
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Hyperglycaemia (high blood sugar)

40-49:

Headache (pain in head)
Arthralgia (joint pain)
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Cough
Diplopia (double vision)
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea exertional (breathlessness or shortness of breath)

50-59:

n/a

60+:

Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
Myasthenia gravis crisis (a paralysis of the respiratory muscles occurs)
Body temperature increased
Cardiac arrest
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Infection
Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)

What are the existing conditions these people have? *

Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 9 people, 32.14%
Secondary Hypertension (elevated blood pressure that results from an underlying, identifiable, often correctable cause): 3 people, 10.71%
Renovascular Hypertension (a syndrome which consists of high blood pressure caused by the kidneys hormonal response): 3 people, 10.71%
Iron Deficiency: 3 people, 10.71%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.71%
Oedema (fluid collection in tissue): 2 people, 7.14%
Mycobacterium Chelonae Infection (bacterial infection): 2 people, 7.14%
Hyperchlorhydria (gastric acid levels are higher in stomach): 2 people, 7.14%
High Blood Pressure: 2 people, 7.14%
Headache (pain in head): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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