Tadalafil and Robitussin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tadalafil (tadalafil) and Robitussin (guaifenesin). Common drug interactions include regurgitation among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Tadalafil and Robitussin. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Tadalafil?

Tadalafil has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 25,548 Tadalafil users. Check the latest studies of Tadalafil.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

On Jul, 12, 2026

21 people who take Tadalafil and Robitussin together, and have interactions are studied.

Tadalafil and Robitussin drug interactions.

What are the common drug interactions of Tadalafil and Robitussin, by gender? *:

female:

Regurgitation (expulsion of material)
Respiratory distress (difficulty in breathing)
Sepsis (a severe blood infection that can lead to organ failure and death)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Thrombocytosis
Viral infection
Vomiting
Weight increased
White blood cell count increased

male:

Dyspnoea (difficult or laboured respiration)
Cough
Arthralgia (joint pain)
Disease progression
Dizziness
Fluid overload (too much fluid in the blood)
Joint swelling
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

What are the common drug interactions of Tadalafil and Robitussin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Sepsis (a severe blood infection that can lead to organ failure and death)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Thrombocytosis
Viral infection
Vomiting
Weight increased
White blood cell count increased
Blood urea increased
Hospitalisation

60+:

Dyspnoea (difficult or laboured respiration)
Cough
Arthralgia (joint pain)
Disease progression
Dizziness
Fluid overload (too much fluid in the blood)
Joint swelling
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 23.81%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 23.81%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 14.29%
Renal Cell Carcinoma (a kidney cancer): 2 people, 9.52%
Immunodeficiency Common Variable: 2 people, 9.52%
Headache (pain in head): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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