Tadalafil and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tadalafil (tadalafil) and Soliris (eculizumab). Common drug interactions include dehydration among females and dysphagia among males.

The phase IV clinical study analyzes what interactions people have when they take Tadalafil and Soliris. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Tadalafil?

Tadalafil has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 25,548 Tadalafil users. Check the latest studies of Tadalafil.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

On Jul, 26, 2026

13 people who take Tadalafil and Soliris together, and have interactions are studied.

Tadalafil and Soliris drug interactions.

What are the common drug interactions of Tadalafil and Soliris, by gender? *:

female:

Dehydration (dryness resulting from the removal of water)
Mobility decreased (ability to move is reduced)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Muscular weakness (muscle weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Pain
Catheter site infection (infection at the site of insertion)
Device occlusion
Haemorrhage (bleeding)
Sepsis (a severe blood infection that can lead to organ failure and death)

male:

Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Syncope (loss of consciousness with an inability to maintain postural tone)
Balance disorder
Cellulitis (infection under the skin)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colitis (inflammation of colon)

What are the common drug interactions of Tadalafil and Soliris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Colorectal cancer (colon cancer or bowel cancer)
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Hepatic steatosis (fatty liver disease)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Rectal cancer (cancer of rectum)
Renal cyst (kidney cyst)
Stress

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Labyrinthitis (inflammation of the labyrinth or inner ear)
Stress
Syncope (loss of consciousness with an inability to maintain postural tone)
Cellulitis (infection under the skin)
Colitis (inflammation of colon)
Dyslalia (inability to articulate comprehensible speech)
Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 8 people, 61.54%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 3 people, 23.08%
Enlarged Prostate: 3 people, 23.08%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 2 people, 15.38%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 7.69%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 7.69%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 1 person, 7.69%
Local Anaesthesia: 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Diabetes: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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