Tagamet and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tagamet (cimetidine) and Acyclovir (acyclovir). Common drug interactions include anaemia among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Tagamet and Acyclovir. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Tagamet?

Tagamet has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,011 Tagamet users. Check the latest studies of Tagamet.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

46 people who take Tagamet and Acyclovir together, and have interactions are studied.

Tagamet and Acyclovir drug interactions.

What are the common drug interactions of Tagamet and Acyclovir, by gender? *:

female:

Anaemia (lack of blood)
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Back pain
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depressive symptom
Device failure
Device related infection

male:

Depression
Dyspnoea (difficult or laboured respiration)
Syncope (loss of consciousness with an inability to maintain postural tone)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Chronic obstructive airways disease
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Polyuria (production of too much dilute urine)
Pyrexia (fever)
Thirst
Diarrhoea

What are the common drug interactions of Tagamet and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Diarrhoea
Headache (pain in head)
Hypertriglyceridaemia (excess of triglycerides in the blood)
Nausea (feeling of having an urge to vomit)
Weight increased
Lipoma (a growth of fatty tissue that slowly develops just under your skin)
Neoplasm growth accelerated (rapid growing tumour)

40-49:

Dyspnoea (difficult or laboured respiration)
Pruritus (severe itching of the skin)
Anaemia (lack of blood)
C-reactive protein increased
Chest pressure sensation (feeling of pressure on chest)
Chest tightness
Culture urine positive
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Dehydration (dryness resulting from the removal of water)
Depression

50-59:

Polyuria (production of too much dilute urine)
Productive cough
Pyrexia (fever)
Thirst
Chronic obstructive airways disease
Ketoacidosis (high concentrations of ketone bodies in blood)
Polydipsia (excessive thirst)
Respiratory rate increased (excess breathing rate/min)
Alopecia (absence of hair from areas of the body)
Asthma

60+:

Osteoporosis (bones weak and more likely to break)
Fatigue (feeling of tiredness)
Loose tooth
Venous insufficiency (poor circulation of blood caused by damaged or enlarged veins)
Arthropathy
Joint effusion (presence of extra fluid in joint covering)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Arteriosclerosis (thickening and hardening of arteries)
Back pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 14 people, 30.43%
Asthma: 5 people, 10.87%
Pain: 4 people, 8.70%
Hiv Infection: 4 people, 8.70%
High Blood Pressure: 3 people, 6.52%
High Blood Cholesterol: 3 people, 6.52%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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