Tagamet and Nitrostat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tagamet (cimetidine) and Nitrostat (nitroglycerin). Common drug interactions include hypertension among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Tagamet and Nitrostat. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Tagamet?

Tagamet has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,011 Tagamet users. Check the latest studies of Tagamet.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.



On Jul, 13, 2026

85 people who take Tagamet and Nitrostat together, and have interactions are studied.

Tagamet and Nitrostat drug interactions.

What are the common drug interactions of Tagamet and Nitrostat, by gender? *:

female:

  1. Hypertension (high blood pressure)
  2. Nocturia (the need to get up in the night to urinate)
  3. Polydipsia (excessive thirst)
  4. Polyuria (production of too much dilute urine)
  5. Somatisation disorder (a long-term (chronic) condition in which a person has physical symptoms that involve more than one part of the body)
  6. Syncope (loss of consciousness with an inability to maintain postural tone)
  7. Eye disorder
  8. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  9. Nephrogenic anaemia (anaemia due to kidney disease)
  10. Renal injury (kidney injury)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Pleural effusion (water on the lungs)
  4. Abscess limb (limb infection)
  5. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  6. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  7. Cervicobrachial syndrome (pain in neck and arm with changing location)
  8. Cystitis (inflammation of the wall of the bladder)
  9. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  10. Dizziness

What are the common drug interactions of Tagamet and Nitrostat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anxiety
  2. Chronic kidney disease
  3. Depression
  4. Renal failure (kidney dysfunction)

30-39:

  1. Arthralgia (joint pain)
  2. Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
  3. Blood glucose increased
  4. Blood sodium decreased
  5. Cardiac disorder
  6. Chronic kidney disease
  7. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  8. Diabetes mellitus inadequate control
  9. Diabetic autonomic neuropathy (diabetes with nerve disorder, painful muscle wasting and weakness)
  10. Diabetic hyperosmolar coma (diabetes coma due to extremely high blood sugar (glucose) levels; extreme lack of water (dehydration))

40-49:

  1. Chronic kidney disease
  2. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  3. Cardiac failure congestive
  4. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Headache (pain in head)
  6. Hypertension (high blood pressure)
  7. Renal failure (kidney dysfunction)
  8. Thrombocytopenia (decrease of platelets in blood)

50-59:

  1. Hypertension (high blood pressure)
  2. Nocturia (the need to get up in the night to urinate)
  3. Polydipsia (excessive thirst)
  4. Polyuria (production of too much dilute urine)
  5. Somatisation disorder (a long-term (chronic) condition in which a person has physical symptoms that involve more than one part of the body)
  6. Syncope (loss of consciousness with an inability to maintain postural tone)
  7. Eye disorder
  8. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  9. Cough
  10. Electrocardiogram abnormal

60+:

  1. Chronic kidney disease
  2. Oedema peripheral (superficial swelling)
  3. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  4. Cervical spinal stenosis (narrowing of the spinal canal in the neck)
  5. Cervicobrachial syndrome (pain in neck and arm with changing location)
  6. Cystitis (inflammation of the wall of the bladder)
  7. Dizziness
  8. Emotional distress
  9. Erectile dysfunction
  10. Gastritis (inflammation of stomach)

What are the existing conditions these people have? *

  1. Pain: 34 people, 40.00%
  2. High Blood Pressure: 27 people, 31.76%
  3. High Blood Cholesterol: 24 people, 28.24%
  4. Diabetes: 17 people, 20.00%
  5. Depression: 17 people, 20.00%
  6. Stable Angina (a constant chest pain): 13 people, 15.29%
  7. Gastric Ulcer (stomach ulcer): 12 people, 14.12%
  8. Stress And Anxiety: 12 people, 14.12%
  9. Inflammation: 10 people, 11.76%
  10. Infection: 9 people, 10.59%

* Approximation only. Some reports may have incomplete information.

Do you take Tagamet and Nitrostat?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tagamet and Nitrostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tagamet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nitrostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tagamet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitrostat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cimetidine and nitroglycerin (the active ingredients of Tagamet and Nitrostat, respectively), and Tagamet and Nitrostat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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