Tagamet and Propofol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tagamet (cimetidine) and Propofol (propofol). Common drug interactions include anaphylactic shock among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Tagamet and Propofol. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Tagamet?

Tagamet has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 9,011 Tagamet users. Check the latest studies of Tagamet.

What is Propofol?

Propofol has active ingredients of propofol. It is often used in colonoscopy abnormal. eHealthMe is studying from 38,224 Propofol users. Check the latest studies of Propofol.

On Jul, 21, 2026

30 people who take Tagamet and Propofol together, and have interactions are studied.

What are the common drug interactions of Tagamet and Propofol, by gender? *:

female:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Back pain
Constipation
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Oxygen saturation decreased
Premature baby

male:

Diarrhoea
Dyspnoea (difficult or laboured respiration)
Asthenia (weakness)
Blood glucose increased
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebral atrophy (decrement in size of brain)
Chest discomfort
Colonic polyp (extra part of colon tissue grow in intestine)
Constipation

What are the common drug interactions of Tagamet and Propofol, by age (0-1 to 60+)? *:

0-1:

Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy)
Cerebral haemorrhage (bleeding within the brain)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Diarrhoea
Feeding disorder neonatal (when newborn refuse to drink milk)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Oedema (fluid collection in tissue)
Premature baby

2-9:

n/a

10-19:

n/a

20-29:

Blood pressure decreased
Blood pressure increased
Ventricular fibrillation (abnormally irregular heart rhythm)

30-39:

Abdominal distension
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cerebral oedema (swelling of brain)
Constipation
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Face oedema (swelling of face)
Haemodynamic instability (disturbances in the blood movement in our body)
Hypertension (high blood pressure)

40-49:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Generalised erythema (redness of the skin all over the body)
Histamine level increased
Hypotension (abnormally low blood pressure)
Oxygen saturation decreased
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Thrombocytopenia (decrease of platelets in blood)
Tryptase increased

50-59:

Diabetes mellitus inadequate control
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysarthria (speech disorder)
Dystonia (abnormal muscle tone)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Endocarditis (inflammation in heart muscle)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Fall
Fluid overload (too much fluid in the blood)
Hyperglycaemia (high blood sugar)

60+:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Asthenia (weakness)
Blood glucose increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebral atrophy (decrement in size of brain)
Chest discomfort
Constipation
Deformity (disfigurement)
Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

Neoplasm Malignant (cancer tumour): 5 people, 16.67%
Nausea (feeling of having an urge to vomit): 3 people, 10.00%
Sedation: 2 people, 6.67%
Renal Cell Carcinoma (a kidney cancer): 2 people, 6.67%
Pain: 2 people, 6.67%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 2 people, 6.67%
Bone Marrow Conditioning Regimen: 2 people, 6.67%
Allergies: 2 people, 6.67%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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