Talwin and Medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Talwin (pentazocine lactate) and Medrol (methylprednisolone). Common drug interactions include abdominal distension among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Talwin and Medrol. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Talwin?

Talwin has active ingredients of pentazocine lactate. It is often used in pain. eHealthMe is studying from 893 Talwin users. Check the latest studies of Talwin.

What is Medrol?

Medrol has active ingredients of methylprednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 24,443 Medrol users. Check the latest studies of Medrol.

On Jul, 25, 2026

12 people who take Talwin and Medrol together, and have interactions are studied.

What are the common drug interactions of Talwin and Medrol, by gender? *:

female:

Abdominal distension
Abdominal pain
Abdominal pain upper
Alanine aminotransferase increased
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthrodesis
Blepharospasm (any abnormal contraction or twitch of the eyelid)
Blood acid phosphatase increased
Blood albumin decreased
Blood calcium decreased

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Aortic calcification (aortic calcification sign of heart valve disease)
Back pain
Balance disorder
Blood cholesterol increased
Blood glucose increased
Blood potassium increased
Blood triglycerides increased
Bradycardia (abnormally slow heart action)
Cardiac failure congestive

What are the common drug interactions of Talwin and Medrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Aseptic necrosis bone
Bone cyst
Arthralgia (joint pain)
Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
Difficulty in walking
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteochondrosis (a family of orthopaedic diseases of the joint that occur in children and adolescents)
Osteonecrosis (death of bone)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Bone disorder

40-49:

Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
Constipation
Cushing's syndrome (obesity, a rounded face, increased fat)
Cushingoid (obesity and weakening of the muscles)
Difficulty in walking
Drug hypersensitivity
Dry mouth
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Faecal impaction

50-59:

Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Atrioventricular block complete (heart block complete)
Back pain
Balance disorder
Blood cholesterol increased
Blood glucose increased
Blood potassium increased
Blood triglycerides increased
Bradycardia (abnormally slow heart action)
Cardiac failure congestive

60+:

Drug hypersensitivity
Arthralgia (joint pain)

What are the existing conditions these people have? *

Rickets (softening of bones): 1 person, 8.33%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 8.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 8.33%
Blood Pressure Abnormal: 1 person, 8.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 8.33%
Drowsiness: 1 person, 8.33%
Dry Eyes (lack of adequate tears): 1 person, 8.33%
Gait Disturbance: 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%
Hypersensitivity: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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