Tamiflu and Aleve drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tamiflu (oseltamivir phosphate) and Aleve (naproxen sodium). Common drug interactions include bronchitis among females and drug hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Tamiflu and Aleve. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Tamiflu?

Tamiflu has active ingredients of oseltamivir phosphate. It is often used in the flu. eHealthMe is studying from 22,209 Tamiflu users. Check the latest studies of Tamiflu.

What is Aleve?

Aleve has active ingredients of naproxen sodium. It is often used in pain. eHealthMe is studying from 70,279 Aleve users. Check the latest studies of Aleve.

On May, 10, 2026

61 people who take Tamiflu and Aleve together, and have interactions are studied.

What are the common drug interactions of Tamiflu and Aleve, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure
Cardiomegaly (increased size of heart than normal)
Cellulitis (infection under the skin)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cough
Dermatitis allergic (inflammation of the skin due allergic reaction)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Drug hypersensitivity

male:

Drug hypersensitivity
Migraine (headache)
Aspartate aminotransferase increased
Blood glucose increased
Blood lactate dehydrogenase increased
Bone density decreased
Chest pain
Chronic kidney disease
Confusional state
Cough

What are the common drug interactions of Tamiflu and Aleve, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Agitation (state of anxiety or nervous excitement)
Anxiety
Confusional state
Depressed mood
Fatigue (feeling of tiredness)
Oral discomfort (pain or irritation in mouth)
Psychotic disorder
Somnolence (a state of near-sleep, a strong desire for sleep)
Throat irritation

20-29:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

30-39:

Abdominal pain upper
Anger
Nausea (feeling of having an urge to vomit)
Pneumonia
Sinusitis (inflammation of sinus)
Asthenia (weakness)
Balance disorder
Blindness
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease

40-49:

Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Bone density decreased
Chronic kidney disease
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Emotional distress
Nasopharyngitis (inflammation of the nasopharynx)
Oedema peripheral (superficial swelling)
Osteonecrosis (death of bone)
Pain in extremity

50-59:

Depressed mood
Emotional distress
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
Hypersensitivity
Lung infection
Osteopenia (a condition where bone mineral density is lower than normal)
Pain in extremity
Psychological trauma
Tumour flare (temporary increase in symptoms from a cancer after starting treatment)
Dyspnoea (difficult or laboured respiration)

60+:

Dizziness
Nausea (feeling of having an urge to vomit)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Migraine (headache)
Night blindness (inability to see in night as day)
Paresis (a condition of muscular weakness)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Vomiting
Chronic kidney disease
Drug hypersensitivity

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 29.51%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 17 people, 27.87%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 9.84%
Thyroid Diseases: 4 people, 6.56%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 6.56%
Fever: 4 people, 6.56%
Drowsiness: 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

Do you take Tamiflu and Aleve?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously