Tamiflu and Cimetidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tamiflu (oseltamivir phosphate) and Cimetidine (cimetidine). Common drug interactions include blood glucose decreased among females and dyskinesia among males.

The phase IV clinical study analyzes what interactions people have when they take Tamiflu and Cimetidine. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Tamiflu?

Tamiflu has active ingredients of oseltamivir phosphate. It is often used in the flu. eHealthMe is studying from 22,209 Tamiflu users. Check the latest studies of Tamiflu.

What is Cimetidine?

Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

16 people who take Tamiflu and Cimetidine together, and have interactions are studied.

Tamiflu and Cimetidine drug interactions.

What are the common drug interactions of Tamiflu and Cimetidine, by gender? *:

female:

  1. Blood glucose decreased
  2. Blood pressure decreased
  3. Drug hypersensitivity
  4. Gastric disorder (disease of stomach)
  5. Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
  6. Pain
  7. Skin exfoliation (removal of the oldest dead skin cells)
  8. Sputum increased
  9. Visual acuity reduced (reduced clearness of vision)
  10. Weight decreased

male:

  1. Dyskinesia (abnormality or impairment of voluntary movement)
  2. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  3. Epstein-barr virus antibody positive
  4. Interleukin-2 receptor increased
  5. Interstitial lung disease
  6. Lung disorder (lung disease)
  7. Lymphocyte stimulation test positive
  8. Rheumatoid factor increased
  9. Speech disorder
  10. Antineutrophil cytoplasmic antibody increased

What are the common drug interactions of Tamiflu and Cimetidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Dyskinesia (abnormality or impairment of voluntary movement)
  2. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  3. Speech disorder
  4. Binocular eye movement disorder

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Blood glucose decreased
  2. Chronic kidney disease
  3. Drug hypersensitivity
  4. Gastric disorder (disease of stomach)
  5. Pain
  6. Skin exfoliation (removal of the oldest dead skin cells)
  7. Visual acuity reduced (reduced clearness of vision)
  8. Weight decreased

60+:

  1. Antineutrophil cytoplasmic antibody increased
  2. Antinuclear antibody increased
  3. Lung disorder (lung disease)
  4. Lymphocyte stimulation test positive
  5. Rheumatoid factor increased
  6. Sputum increased
  7. Blood lactate dehydrogenase increased
  8. Blood pressure decreased
  9. Carcinoembryonic antigen increased
  10. Cytomegalovirus test positive

What are the existing conditions these people have? *

  1. High Blood Pressure: 6 people, 37.50%
  2. Multiple Myeloma (cancer of the plasma cells): 1 person, 6.25%
  3. Inflammation: 1 person, 6.25%
  4. Infection: 1 person, 6.25%
  5. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Tamiflu and Cimetidine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tamiflu and Cimetidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tamiflu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cimetidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tamiflu and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cimetidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on oseltamivir phosphate and cimetidine (the active ingredients of Tamiflu and Cimetidine, respectively), and Tamiflu and Cimetidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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