Tamiflu and Prograf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tamiflu (oseltamivir phosphate) and Prograf (tacrolimus). Common drug interactions include blood triglycerides increased among females and subarachnoid haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Tamiflu and Prograf. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Tamiflu?

Tamiflu has active ingredients of oseltamivir phosphate. It is often used in the flu. eHealthMe is studying from 22,209 Tamiflu users. Check the latest studies of Tamiflu.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

On Jul, 20, 2026

50 people who take Tamiflu and Prograf together, and have interactions are studied.

What are the common drug interactions of Tamiflu and Prograf, by gender? *:

female:

Blood triglycerides increased
Blood urea increased
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Cardiac arrest
Chronic kidney disease
Conjunctivitis allergic (inflammation of the conjunctiva due to allergy)
Constipation
Cystitis (inflammation of the wall of the bladder)
Cytomegalovirus hepatitis (virus infection of liver)
Double stranded dna antibody positive

male:

Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Hydronephrosis (water inside the kidney)
Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
Herpes zoster
Tachypnoea (a condition of rapid breathing over 20 per minute)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Multi-organ failure (multisystem organ failure)
Nephrosclerosis (hardening of the kidney due to renovascular disease)
Renal failure (kidney dysfunction)

What are the common drug interactions of Tamiflu and Prograf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Transplant rejection (a transplant material is not worked)

10-19:

Renal impairment (severely reduced kidney function)
Headache (pain in head)
Infection
Pyrexia (fever)

20-29:

Urine output decreased
Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)
Abdominal pain upper
Blood pressure increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Double stranded dna antibody positive
Drug ineffective
Headache (pain in head)
Immunosuppressant drug level increased
Iron deficiency anaemia

30-39:

Neoplasm skin (skin tumour)
Oral candidiasis (fungal infection of mouth)
Osteonecrosis (death of bone)
Pancreatitis (inflammation of pancreas)
Periodontal disease (disease that attacks the gum and bone and around the teeth)
Pneumonia
Pneumonia bacterial (pneumonia associated with bacterial infection)
Rash generalised (rash on most of body parts)
Rash pruritic (redness with itching)
Renal failure (kidney dysfunction)

40-49:

Circulatory collapse
Pneumonia bacterial (pneumonia associated with bacterial infection)
Ascites (accumulation of fluid in the abdominal cavity)
Coma (state of unconsciousness lasting more than six hours)
Depressed level of consciousness
Hepatic failure (liver failure)
Hepatitis c
Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)

50-59:

Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Pulmonary oedema (fluid accumulation in the lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Cytomegalovirus enterocolitis (virus infection of intestine and colon)
Chronic kidney disease
Cytomegalovirus hepatitis (virus infection of liver)
Gastritis (inflammation of stomach)
Glomerulonephritis membranous (nephritis with inflammation of the capillary loops in the renal glomeruli)

60+:

Hydronephrosis (water inside the kidney)
Renal disorder (kidney disease)
Lung infection
Oesophageal infection
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the existing conditions these people have? *

Pain: 8 people, 16.00%
Stress And Anxiety: 7 people, 14.00%
High Blood Pressure: 7 people, 14.00%
Gastritis (inflammation of stomach): 6 people, 12.00%
Diarrhea: 6 people, 12.00%
Nausea (feeling of having an urge to vomit): 5 people, 10.00%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 5 people, 10.00%
Depression: 5 people, 10.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 8.00%
Oedema (fluid collection in tissue): 4 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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