Tapazole and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tapazole (methimazole) and Reglan (metoclopramide hydrochloride). Common drug interactions include cyanosis among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Tapazole and Reglan. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Tapazole?

Tapazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 2,477 Tapazole users. Check the latest studies of Tapazole.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

On Jul, 17, 2026

19 people who take Tapazole and Reglan together, and have interactions are studied.

What are the common drug interactions of Tapazole and Reglan, by gender? *:

female:

Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Cystitis bacterial (inflammation of the wall of the bladder by bacteria escherichia coli)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dermal cyst
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diarrhoea
Diastolic dysfunction
Diplopia (double vision)
Dysuria (painful or difficult urination)
Encephalopathy (functioning of the brain is affected by some agent or condition)

male:

Anaemia (lack of blood)
Oedema peripheral (superficial swelling)
Blood urea increased
Carbon dioxide decreased
Cardioactive drug level decreased
Dysplasia (enlargement of an organ or tissue)
Haematocrit decreased
Haemoglobin decreased
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

What are the common drug interactions of Tapazole and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cholecystitis chronic (long lasting infection of gallbladder)
Gallbladder injury
Injury
Pain

30-39:

Nephrogenic fibrosing dermopathy (involves fibrosis of skin, joints, eyes due to kidney disease)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Alopecia (absence of hair from areas of the body)
Dyspnoea (difficult or laboured respiration)
Feeling jittery

40-49:

n/a

50-59:

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Melaena (the passage of black, tarry stools)
Blood cholesterol increased
Cyst (a closed sac)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Gastric ulcer (stomach ulcer)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hyperglycaemia (high blood sugar)
Hyperlipidaemia (presence of excess lipids in the blood)
Limb injury

60+:

Arthralgia (joint pain)
Blood urea increased
Blood glucose increased
Blood pressure decreased
Carbon dioxide decreased
Cardioactive drug level decreased
Drug ineffective
Dysplasia (enlargement of an organ or tissue)
Haematocrit decreased
Haemoglobin decreased

What are the existing conditions these people have? *

Pain: 7 people, 36.84%
Stress And Anxiety: 4 people, 21.05%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 15.79%
Chest Pain: 3 people, 15.79%
Depression: 3 people, 15.79%
Muscle Spasms (muscle contraction): 3 people, 15.79%
Nausea (feeling of having an urge to vomit): 3 people, 15.79%
Nausea And Vomiting: 2 people, 10.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.53%
Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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