Capecitabine and Tarceva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Capecitabine (capecitabine) and Tarceva (erlotinib hydrochloride). Common drug interactions include death among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Capecitabine and Tarceva. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Capecitabine?

Capecitabine has active ingredients of capecitabine. eHealthMe is studying from 59,495 Capecitabine users. Check the latest studies of Capecitabine.

What is Tarceva?

Tarceva has active ingredients of erlotinib hydrochloride. It is often used in lung cancer. eHealthMe is studying from 31,036 Tarceva users. Check the latest studies of Tarceva.

On Nov, 18, 2025

35 people who take Capecitabine and Tarceva together, and have interactions are studied.

Capecitabine and Tarceva drug interactions.

What are the common drug interactions of Capecitabine and Tarceva, by gender? *:

female:

Death
Constipation
Diarrhoea
Flatulence (flatus expelled through the anus)
Nausea (feeling of having an urge to vomit)
Chills (felling of cold)
Cough
Decreased appetite
Neuropathy peripheral (surface nerve damage)
Abdominal discomfort

male:

Diarrhoea
Vomiting
Weight decreased
Ascites (accumulation of fluid in the abdominal cavity)
Constipation
Decreased appetite
Nausea (feeling of having an urge to vomit)
Hospitalisation
Rash
Skin fissures (a crack in the skin)

What are the common drug interactions of Capecitabine and Tarceva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood albumin decreased
Constipation
Cytomegalovirus infection
Epistaxis (bleed from the nose)
Full blood count decreased
Idiopathic thrombocytopenic purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting)
Metastases to pancreas (cancer spreads to pancreas)
Oedema peripheral (superficial swelling)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Rash

40-49:

Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Blood bilirubin increased
Cachexia (loss of weight)
Constipation
Decreased appetite
Hypotension (abnormally low blood pressure)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Intestinal perforation (complete penetration of the wall of the intestine)

50-59:

Death
Hospitalisation
Nausea (feeling of having an urge to vomit)
Vomiting

60+:

Diarrhoea
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Disease progression
Weight decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chills (felling of cold)
Constipation
Cough
Flatulence (flatus expelled through the anus)
Neuropathy peripheral (surface nerve damage)

What are the existing conditions these people have? *

Pancreatic Carcinoma (pancreatic cancer): 11 people, 31.43%
Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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