Tarceva and Milk thistle drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tarceva (erlotinib hydrochloride) and Milk thistle (milk thistle). Common drug interactions include dysphonia among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Tarceva and Milk thistle. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Tarceva?

Tarceva has active ingredients of erlotinib hydrochloride. It is often used in lung cancer. eHealthMe is studying from 31,036 Tarceva users. Check the latest studies of Tarceva.

What is Milk thistle?

Milk thistle has active ingredients of milk thistle. It is often used in fatty liver. eHealthMe is studying from 5,057 Milk thistle users. Check the latest studies of Milk thistle.



On Jul, 21, 2026

19 people who take Tarceva and Milk thistle together, and have interactions are studied.

Tarceva and Milk thistle drug interactions.

What are the common drug interactions of Tarceva and Milk Thistle, by gender? *:

female:

  1. Dysphonia (speech disorder attributable to a disorder of phonation)
  2. Hand fracture
  3. Muscle spasms (muscle contraction)
  4. Pain
  5. Tooth disorder (tooth disease)
  6. Trichorrhexis (a condition in which the hairs break)
  7. Weight increased
  8. Cerebral disorder (brain disease)
  9. Localised infection (infection at the single location)
  10. Mass

male:

  1. Death
  2. Fatigue (feeling of tiredness)
  3. Rash
  4. Rib fracture
  5. Skin ulcer
  6. Sunburn
  7. Adverse drug reaction
  8. Blood urine present
  9. Chest pain
  10. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)

What are the common drug interactions of Tarceva and Milk Thistle, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Dysphonia (speech disorder attributable to a disorder of phonation)
  2. Hand fracture
  3. Muscle spasms (muscle contraction)
  4. Pain
  5. Tooth disorder (tooth disease)
  6. Trichorrhexis (a condition in which the hairs break)
  7. Weight increased
  8. Cerebral disorder (brain disease)
  9. Localised infection (infection at the single location)
  10. Mass

50-59:

  1. Death

60+:

  1. Death
  2. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  3. Vomiting
  4. Adverse drug reaction
  5. Erythema (redness of the skin)
  6. Fatigue (feeling of tiredness)
  7. Peripheral swelling
  8. Pruritus (severe itching of the skin)
  9. Rib fracture
  10. Skin ulcer

What are the existing conditions these people have? *

  1. Lung Neoplasm Malignant (cancer tumour of lung): 7 people, 36.84%
  2. Neoplasm Malignant (cancer tumour): 6 people, 31.58%
  3. Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 5 people, 26.32%
  4. Lung Carcinoma Cell Type Unspecified Stage I (the lung cancer is small and hasn't spread to the lymph nodes): 5 people, 26.32%
  5. Metastases To Bone (cancer spreads to bone): 5 people, 26.32%
  6. Muscle Spasms (muscle contraction): 5 people, 26.32%
  7. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 5 people, 26.32%
  8. Vestibular Disorder (disorders of the body's balance (vestibular) system in the inner ear): 5 people, 26.32%
  9. Panic Disorder: 5 people, 26.32%
  10. Tinnitus (a ringing in the ears): 5 people, 26.32%

* Approximation only. Some reports may have incomplete information.

Do you take Tarceva and Milk thistle?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tarceva and Milk thistle:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tarceva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Milk thistle:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tarceva and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Milk thistle and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on erlotinib hydrochloride and milk thistle (the active ingredients of Tarceva and Milk thistle, respectively), and Tarceva and Milk thistle (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: