Tarceva and Phenytoin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tarceva (erlotinib hydrochloride) and Phenytoin (phenytoin). Common drug interactions include acne among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Tarceva and Phenytoin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Tarceva?

Tarceva has active ingredients of erlotinib hydrochloride. It is often used in lung cancer. eHealthMe is studying from 31,036 Tarceva users. Check the latest studies of Tarceva.

What is Phenytoin?

Phenytoin has active ingredients of phenytoin. It is often used in epilepsy. eHealthMe is studying from 15,753 Phenytoin users. Check the latest studies of Phenytoin.

On Jul, 31, 2026

13 people who take Tarceva and Phenytoin together, and have interactions are studied.

Tarceva and Phenytoin drug interactions.

What are the common drug interactions of Tarceva and Phenytoin, by gender? *:

female:

Acne (skin problems that cause pimples)
Oedema peripheral (superficial swelling)
Anticonvulsant drug level increased
Ataxia (loss of full control of bodily movements)
Balance disorder
Dizziness
Drug level below therapeutic
Dysarthria (speech disorder)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Malignant neoplasm progression (cancer tumour came back)

male:

Pyrexia (fever)
Rash
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Asthma
Blood creatinine increased
Blood urea increased
Bronchial carcinoma (lung cancer)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Decreased appetite

What are the common drug interactions of Tarceva and Phenytoin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anticonvulsant drug level increased
Dysphagia (a condition in which swallowing is difficult or painful)
Pyrexia (fever)
Rash
Stomatitis (inflammation of mucous membrane of mouth)
Ataxia (loss of full control of bodily movements)
Balance disorder
Dizziness
Drug level below therapeutic
Dysarthria (speech disorder)

60+:

Oedema peripheral (superficial swelling)
Acne (skin problems that cause pimples)
Asthenia (weakness)
Asthma
Blood creatinine increased
Blood urea increased
Bronchial carcinoma (lung cancer)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Decreased appetite
Depressed level of consciousness

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 5 people, 38.46%
Metastases To Central Nervous System (cancer spreads to central nervous system): 2 people, 15.38%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 15.38%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 2 people, 15.38%
Thyroid Diseases: 1 person, 7.69%
Swelling: 1 person, 7.69%
Rectal Cancer Metastatic (cancer of rectum spreads to other): 1 person, 7.69%
Pain: 1 person, 7.69%
Neoplasm Malignant (cancer tumour): 1 person, 7.69%
Lung Adenocarcinoma Metastatic (a form of non-small cell lung cancer spreads to other part): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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