Tasigna and Olanzapine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tasigna (nilotinib hydrochloride monohydrate) and Olanzapine (olanzapine). Common drug interactions include vertebral artery stenosis among females and eyelid oedema among males.
The phase IV clinical study analyzes what interactions people have when they take Tasigna and Olanzapine. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Tasigna?
Tasigna has active ingredients of nilotinib hydrochloride monohydrate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 31,535 Tasigna users. Check the latest studies of Tasigna.
What is Olanzapine?
Olanzapine has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 69,242 Olanzapine users. Check the latest studies of Olanzapine.
20 people who take Tasigna and Olanzapine together, and have interactions are studied.

What are the common drug interactions of Tasigna and Olanzapine, by gender? *:
female:
- Vertebral artery stenosis (abnormal narrowing of vertebral artery)
- Arthralgia (joint pain)
- Carotid arteriosclerosis (plaque deposition in artery)
- Carotid artery occlusion (artery blockage)
- Carotid bruit (sound heard over the carotid artery area during auscultation)
- Carotid intima-media thickness increased (increased thickness of carotid artery muscle)
- Cerebral artery stenosis (hardening of brain blood vessels)
- Drug intolerance (drug sensitivity)
- Gait disturbance
- Myalgia (muscle pain)
male:
- Eyelid oedema (eyelids are swollen and contain excessive fluid)
- Folliculitis (infection of hair root)
- Non-cardiac chest pain
- Rash
- Swelling
What are the common drug interactions of Tasigna and Olanzapine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Eyelid oedema (eyelids are swollen and contain excessive fluid)
- Folliculitis (infection of hair root)
- Non-cardiac chest pain
- Rash
- Swelling
30-39:
n/a
40-49:
- Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body)
- Lymphoma (cancer that begins in immune system cells)
- Blood bilirubin increased
- Blood lactate dehydrogenase increased
- Glomerular filtration rate decreased
- Haemoglobin decreased
50-59:
- Carotid artery stenosis (narrowing of carotid artery)
- Basilar artery stenosis (abnormal narrowing of basilar artery)
- Cerebral artery stenosis (hardening of brain blood vessels)
- Drug intolerance (drug sensitivity)
- Gait disturbance
- Myalgia (muscle pain)
- Nocturnal dyspnoea (attacks of severe shortness of breath and coughing that generally occur at night)
- Vertebral artery hypoplasia (incomplete or arrested development of vertebral artery)
- Disease progression
- Subclavian artery stenosis (the abnormal narrowing of subclavian artery)
60+:
n/a
What are the existing conditions these people have? *
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 17 people, 85.00%
- Psychotic Disorder: 10 people, 50.00%
- Depression: 5 people, 25.00%
- Chronic Myeloid Leukaemia (In Remission): 2 people, 10.00%
* Approximation only. Some reports may have incomplete information.
Do you take Tasigna and Olanzapine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Tasigna (31,535 reports)
- Olanzapine (69,242 reports)
Browse all drug interactions of Tasigna and Olanzapine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tasigna:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Olanzapine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tasigna and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Olanzapine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on nilotinib hydrochloride monohydrate and olanzapine (the active ingredients of Tasigna and Olanzapine, respectively), and Tasigna and Olanzapine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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