Taurine and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Taurine (taurine) and Melatonin (melatonin). Common drug interactions include anxiety among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Taurine and Melatonin. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Taurine?

Taurine has active ingredients of taurine. eHealthMe is studying from 1,016 Taurine users. Check the latest studies of Taurine.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,213 Melatonin users. Check the latest studies of Melatonin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

93 people who take Taurine and Melatonin together, and have interactions are studied.

Taurine and Melatonin drug interactions.

What are the common drug interactions of Taurine and Melatonin, by gender? *:

female:

  1. Anxiety
  2. Depression
  3. Diarrhoea
  4. Headache (pain in head)
  5. Cough
  6. Agitation (state of anxiety or nervous excitement)
  7. Blood cholesterol increased
  8. Decreased appetite
  9. Hot flush (sudden feelings of heat)
  10. Hypertension (high blood pressure)

male:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Fall
  3. Anticonvulsant drug level below therapeutic
  4. Anxiety
  5. Arachnoiditis (neuropathic disease caused by inflammation of the arachnoid)
  6. Arteriovenous fistula
  7. Asthenia (weakness)
  8. Back pain
  9. Blood pressure diastolic decreased
  10. Blood pressure diastolic increased

What are the common drug interactions of Taurine and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Abnormal behaviour
  2. Anticonvulsant drug level below therapeutic
  3. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  4. Pyrexia (fever)
  5. Retinal injury (injury to retina)
  6. Rhinorrhoea (watery mucus discharge from the nose)
  7. Aggression
  8. Conjunctivitis (pink eye)
  9. Cough
  10. Ear infection

10-19:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Diarrhoea
  3. Ovarian cyst (fluid filled sac of the ovary)
  4. Rash
  5. Agitation (state of anxiety or nervous excitement)
  6. Blood cholesterol increased
  7. Decreased appetite
  8. Dysgeusia (disorder of the sense of taste)
  9. Loss of consciousness
  10. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)

20-29:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Atonic seizures (minor type of seizure)
  3. Drooling (drop saliva uncontrollably from the mouth)
  4. Fall
  5. Oral pain
  6. Abdominal discomfort
  7. Agitation (state of anxiety or nervous excitement)
  8. Body temperature fluctuation
  9. Bowel movement irregularity
  10. Bruxism (habitual grinding of the teeth, typically during sleep)

30-39:

  1. Alopecia (absence of hair from areas of the body)
  2. Anxiety
  3. Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
  4. Confusional state
  5. Disability
  6. Fatigue (feeling of tiredness)
  7. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  8. Neuralgia (pain in one or more nerves)
  9. Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
  10. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

40-49:

  1. Hypertension (high blood pressure)
  2. Rosacea (a skin condition that causes facial redness)
  3. Arthralgia (joint pain)
  4. Asthenia (weakness)
  5. Cerebral disorder (brain disease)
  6. Chills (felling of cold)
  7. Chronic kidney disease
  8. Depression
  9. Dizziness
  10. Fatigue (feeling of tiredness)

50-59:

  1. Bradycardia (abnormally slow heart action)
  2. Cellulitis (infection under the skin)
  3. Cervical cord compression (compression of spinal cord at site of cervical vertebrae)
  4. Cervical radiculopathy (disturbance of nerve function that causes pain in the upper body)
  5. Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
  6. Clumsiness (a lack of coordination or elegance)
  7. Constipation
  8. Csf protein increased
  9. Cystitis (inflammation of the wall of the bladder)
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

60+:

  1. Sinusitis (inflammation of sinus)
  2. Systemic mycosis (fungal infections of the body)
  3. Weight decreased
  4. Adverse drug reaction
  5. Anaemia postoperative
  6. Arrhythmia (irregular heartbeat)
  7. Arthralgia (joint pain)
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Atrophic vulvovaginitis (inflammation of the vulva)
  10. Bacteraemia (presence of bacteria in the blood)

What are the existing conditions these people have? *

  1. Sleep Disorder: 9 people, 9.68%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 8.60%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 8.60%
  4. Hereditary Angioedema (recurrent episodes of severe swelling): 8 people, 8.60%
  5. Immunodeficiency Common Variable: 7 people, 7.53%
  6. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 6 people, 6.45%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 6.45%
  8. Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 5 people, 5.38%
  9. Drowsiness: 5 people, 5.38%
  10. Astrocytoma, Low Grade (low grade tumour of the brain that originate in a particular kind of glial-cells): 5 people, 5.38%

* Approximation only. Some reports may have incomplete information.

Do you take Taurine and Melatonin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Taurine and Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Taurine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Taurine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Melatonin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on taurine and melatonin (the active ingredients of Taurine and Melatonin, respectively), and Taurine and Melatonin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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