Tazidime and Emend drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tazidime (ceftazidime) and Emend (aprepitant). Common drug interactions include toxic skin eruption among females and angioedema among males.
The phase IV clinical study analyzes what interactions people have when they take Tazidime and Emend. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.
What is Tazidime?
Tazidime has active ingredients of ceftazidime. eHealthMe is studying from 10,409 Tazidime users. Check the latest studies of Tazidime.
What is Emend?
Emend has active ingredients of aprepitant. It is often used in nausea. eHealthMe is studying from 13,741 Emend users. Check the latest studies of Emend.
24 people who take Tazidime and Emend together, and have interactions are studied.

What are the common drug interactions of Tazidime and Emend, by gender? *:
female:
- Toxic skin eruption (skin breakdown due to toxic substance)
- Febrile neutropenia (fever with reduced white blood cells)
- Nephritic syndrome (a collection of signs (known as a syndrome) associated with disorders affecting the kidneys, more specifically glomerular disorders)
- Pulmonary alveolar haemorrhage (acute bleeding)
- Septic shock (shock due to blood infection)
- Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Erythema (redness of the skin)
male:
- Angioedema (rapid swelling of the dermis)
- Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
- Hypersensitivity
- Oedema mouth (swelling of mouth)
- Oral pain
- Stomatitis (inflammation of mucous membrane of mouth)
- Abdominal pain
- Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
What are the common drug interactions of Tazidime and Emend, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
- Febrile neutropenia (fever with reduced white blood cells)
- Neuropathy peripheral (surface nerve damage)
- Stomatitis (inflammation of mucous membrane of mouth)
- Vocal cord paralysis
10-19:
- Angioedema (rapid swelling of the dermis)
- Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
- Hypersensitivity
- Oedema mouth (swelling of mouth)
- Oral pain
- Stomatitis (inflammation of mucous membrane of mouth)
- Drug clearance decreased
- Drug level increased
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
20-29:
- Febrile neutropenia (fever with reduced white blood cells)
30-39:
- Nephritic syndrome (a collection of signs (known as a syndrome) associated with disorders affecting the kidneys, more specifically glomerular disorders)
- Pulmonary alveolar haemorrhage (acute bleeding)
- Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
- Intestinal obstruction
- Leukopenia (less number of white blood cells in blood)
- Neutropenia (an abnormally low number of neutrophils)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Septic shock (shock due to blood infection)
- Abdominal pain
- Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
40-49:
- Anaemia (lack of blood)
- Fatigue (feeling of tiredness)
- Febrile neutropenia (fever with reduced white blood cells)
- Muscular weakness (muscle weakness)
- White blood cell count decreased
50-59:
- Erythema (redness of the skin)
- Pruritus (severe itching of the skin)
- Aplasia (defective development or congenital absence of an organ or tissue)
- Bacteraemia (presence of bacteria in the blood)
- Toxic skin eruption (skin breakdown due to toxic substance)
60+:
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Vomiting
- Bone marrow failure
- Oral intake reduced
- Septic shock (shock due to blood infection)
What are the existing conditions these people have? *
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 25.00%
- Septic Shock (shock due to blood infection): 5 people, 20.83%
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 4 people, 16.67%
- Insomnia (sleeplessness): 3 people, 12.50%
- Breast Cancer: 3 people, 12.50%
- Stomatitis (inflammation of mucous membrane of mouth): 2 people, 8.33%
- Oropharyngeal Candidiasis (fungal infection of oropharynx): 2 people, 8.33%
- Gastric Ulcer (stomach ulcer): 2 people, 8.33%
- Cough: 2 people, 8.33%
- Bacteraemia (presence of bacteria in the blood): 2 people, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Tazidime and Emend?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tazidime and Emend:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tazidime:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Emend:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tazidime and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Emend and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Chen F, Zhan Z, "Severe drug-induced immune haemolytic anaemia due to ceftazidime", Blood Transfusion, 2014 Jan .
- Chen F, Zhan Z, "Severe drug-induced immune haemolytic anaemia due to ceftazidime", Blood Transfusion, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on ceftazidime and aprepitant (the active ingredients of Tazidime and Emend, respectively), and Tazidime and Emend (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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